The Effect Of Resistance Training Of Different Intensity On Blood Lipids And Interleukin 6 In Older Chinese Overweight And Obese Women

Objective:Resistance exercise, traditionally used as the type of exercise to stimulate muscle growth,has rarely been linked with metabolic health until recently. Recent years, a growing number of studies have shown the beneficial effects of resistance training beyond enhancing the mass and strength of muscles, including improving individuals’ metabolic health as demonstrated by changes in blood glucose levels, lipids profiles, and chronic inflammatory status. However, better utilization of resistance exercise in preventing and treating metabolic disorders needs a better understanding of the various influencing factors, especially the training intensity. Whether different intensities have different effect on the promotion of metabolic health? This important question hasn’t yet been clearly answered. In view of this, we carried out the present study, where mid-high(70-80% 1RM) and low(50-60% 1RM) intensities were used to train the older overweight and obese women for 16 weeks. Specifically, we sought to determine whether the resistance training of high or low intensity is more effective in improving the blood lipids profiles and chronic inflammation.Methods:Overweight or obese women with a BMI 3 25 or more aged 60 years and older were recruited. Subjects were randomly assigned to two training groups. Two groups were subjected to resistance exercise training of two different intensities(70-80% 1RM or 50-60% 1RM), three times a week for 16 weeks. Before and after the training, a fasting blood sample was collected from each subject, blood lipids levels and the levels of chronic inflammatory factors,hypersensitive c-reactive protein(CRP) and interleukin-6(IL6), were measured. SPSS20.0 was used to perform statistical analysis of data. Repeated measure analysis of variance was conducted to test the differential training effect at different intensities. Significant level was set at P ￡0.05.Result:Repetitive measure analysis of variance revealed that the interaction of the within-group factor(time) and the between-group factor(intensity) for all outcome measures were not significant, indicating that training-induced effects on blood lipids and inflammatory factors in our subjects were similar between high and low intensity(70~80$1RM vs. 50~60%1RM). Group paired t test revealed that both the mid-high and low intensity resistance training induced significant decreases in total cholesterol, low-density lipoprotein cholesterol and IL6(P < 0. 05).Conclusions:Intensity of resistance training does not have a significant impact on the training effect on blood lipids profiles and chronic inflammatory status in older Chinese overweight or obese women. Irrespective of the different intensities applied, resistance exercise training is effective in lowing blood lipids levels and inflammatory status in older Chinese women, which suggests that resistance exercise training can be effectively used to protect the cardiovascular system and delay the onset of diabetes and its complications among high-risk individuals.