| Objective To explore the characteristics of cognitive function changes in patients with acute middle cerebral artery occlusion after interventional treatment. Methods 10 cases of recovery well patients with acute middle cerebral artery occlusion(90d mRS≤2) after interventional treatment(case group) and 10 age-matched normal controls( control group)were collected. Firstly,the cognitive function for all subjects were evaluated by Chinese version of Montreal Cognitive Assessment Scale.Afterwards,the two groups underwent standard resting state functional MRI(fMRI) sacn.All dates were analysed by use of Regional Homogeneity(ReHo).Results 1.Compared with control group,the patients in case group had differences in visual visual spatial and executive function,language and delayed recall aspects.There was no difference in naming,attention,abstraction and directed cognitive aspects. 2.Compared with control group,case group showed significantly decreased ReHo in the left precentral gyrus, left frontal gyrus,right lingual gyrus,left lingual gyrus, left middle temporal gyrus,left praecuneus,left posterior lobe of cerebellum, right anterior lobe of cerebellum and right posterior lobe of cerebellum,and increased ReHo in left medial frontal gyrus,right superior temporal gyrus and left hippocampus. Conclusions There were still cognitive impairment in recovery well patients with acute middle cerebral artery occlusion after interventional treatment,and the rest-state brain function was abnormal in these patients,and the increased ReHo in some brain area may reflect stress-induced brain protection of acute middle cerebral artery occlusion and partial compensatory response. |
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