Research On Thrombosis Principle Of Left Atrial Appendage In Patients With Atrial Fibrillation

Objective: To investigate the relationship between left Atrial appendage morp hology and function changes of left atrial appendage(LAA) thrombosis in patients with atrial fibrillation(AF). Mothod: 114 patients with AF and 54 controls were examined with real-time three-dimensional transesophageal echocardiography(RT3D-TEE). Left Airail Appendage Length(LAA-L), orifice area(LAA-O), volume(LAA-V) and left atrial appendage velocity(LAA-v), left atrial volume(LA-V), left atri al appendage ejection fraction(LAA-EF) were observed and compared with those of the contral group.AF patients were divided into no spontaneous contrast subgro up(NSEC), spontaneous subgroup(SEC) and thrombus subgroup(TH). Thoses ind icators were also observed between NSEC, SEC and TH subgroup.Date were calc ulated and analysised. Result: Values of LAA-L, LAA-0, LAA-V, LA-V were stati stically higher in patients with AF than in patients with non-AF, but LAA-v, LA A-EF were Lower in patients with AF than in patients with non-AF. LAA-O, LA A-v and LA-V in TH subgroub were higher than in NSEC subgroub(P<0.05). L AA-L and LAA-EF of the three subgroups were different from each other(P<0.05), LAA-v of TH and SEC subgroups were lower than that of NSEC subgroup(P<0.05). Conclusion: Thrombosis in AF is closely related with the morphology and function changes of LAA.