The Value Of Three-dimensional Spot Tracking Imaging Technology In Grading The Impact Of Myocardial Systolic Function In Patients With Lung Cancer Received Chemotherapy

Objective Nearly 50 years the incidence of lung cancer increased significantly,For clinical treatment of lung cancer chemotherapy is still the main means, especially for the lost opportunities of surgical operation in treating patients.However, that the side effects of chemotherapy drugs inevitably limits the application of dose of drug,and the patient’s physical and mental damage, affect the treatment effect.Chemotherapy drugs of myocardial damage is one of the side effects.To assess the value of real-time threedimensional spot tracking imaging(RT-3DSTI) technology in grading the impact of left ventricular myocardial systolic function in patients with lung cancer received chemotherapy,and guide the clinical treatment in this literature.Methods 41 patients with NCLC were enrolled, every patient had three stages,before chemotherapy, during chemotherapy and after chemotherapy,and every stage was regarded as a group.The Inner diameter and thickness of left ventricle were measured by two-dimensional ultrasound,the left ventricular global area strain(GAS),global longitudinal strain(GLS),global circumferential strain(GCS),global radial strain(GRS) and left volumes ejection fraction(LVEF), HR and strain curve were obtained by RT-3DSTI,the above parameters and strain curve were compared and analysed.Results 1.The values of GAS,GLS,GCS,LVEF of three groups were all decreased as with the proceeding of chemotherapy,and the diminution is gradual.2.It all showed statistical differences between before chemotherapy groups and chemotherapy groups, chemotherapy agroups and after chemotherapy groups,before chemotherapy agroups and after chemotherapy groups in the values of GAS,GLS(P<0.05).3.It showed statistical differences between chemotherapy groups and chemotherapy groups, before chemotherapy agroups and after chemotherapy groups in the values of GCS(P<0.05).4.The GRS comparison shows differences between 3 groups is not obvious, there were no statistical significance5.The differences of the values of GAS(r=0.58,P<0.01),GLS(r=0.36,P<0.05)were both positively related to the differences of the values LVEF’s between before chemotherapy groups and after chemotherapy groups.6.The GAS was a positive correlation with GLS and GCS and GCS was a positive correlation with GLS in the three groups(r=0.71,r=0.70,r=0.65,P<0.05).Conclusion 1.RT-3DSTI has a great significance in dignosing the early damage of chemical drugs in patients with lung cancer, evaluating the systolic function of left ventricula, guiding clinical treatment.2.With the cycles of chemotherapy, the strain parameters gradually reducing, and myocardial damage is also gradually increasing.