Clinical Significance Of Fungal Culture In The Lower Respiratory Tract Of Patients With Severe Cases

Objective: To investigate the predictive factors of fungal colonization or infection in patients with severe lower respiratory tract infection, and to provide evidence for clinical judgment. Methods: 2013 October to October 2015 in respiratory IC U of the First Affiliated Hospital of Xinjiang Medical University respiratory specimens of fungi isolated positive patients, divided into pulmonary fungal infection group( fungal infection group) and pulmonary fungal value group(fungal colonization group), were statistically analyzed. Results: A total of 293 patients, 143 cases of infection group, 150 cases of colonization group. Single factor analysis and logistic regression model analysis showed that long-term use of Glucocorticoid(equal to or more than 14 days), long-term use of broad-spectrum antibiotics(equal to or more than 14 days), based disease complicated with tumor, diabetes, chronic lung disease, clinical manifestations of respiratory symptoms, fever, and dyspnea, and C T findings of nodules and fast like shadows in fungal infection and value judgment in difference has statistical significance(all P < 0.05). These clinical and imaging features of the ROC curve area show that long-term use of corticosteroids, long-term use of broad-spectrum antibiotics, nodules and block the area under the shadow of the curve is more than 0.6. Conclusion: Whether the results of BALF isolation are fungal infections, mainly depends on whether patients have high risk factors for long-term use of corticosteroids or broad-spectrum antibiotics, as well as imaging of nodules and block shadows.