The Clinical Studies On The Correlation Between Carotid Intima-media Thickness And Carotid Artery Plague And Coronary Artery Disease And Its Risk Factors

Objective:We aimed to o explore the relationship between carotid intima-media thickness and carotid artery plague and coronary artery disease and its risk factors.Methods:The study population consisted of 160 consecutive patients who saw a doctor in our vasculocardiology department between 2012 and 2015.All subjects(101 males,59 females)with an average age of 58+-19 years old underwent carotid color-coded Doppler ultrasound 1week before or after coronary angiography. The carotid intima-media thickness over 1.0mm,the presence of carotid artery plaque and coronary artery stenosis more than 50% is positive results。Making a comparision and analysis of the results of carotid color-coded Doppler ultrasound and coronary angiography,then compare the positive and negative results of carotid color-coded Doppler ultrasound according to coronary artery disease risk factors( sex,age,plasma glucose,plasma lipids,blood pressure,etc).Reasults:The number of patients with carotid intima-media thickness and carotid artery plaque was 122 which accounted for 76.3% of total patients.The percentage of patients with coronary artery stenosis more than 50%(n=93) was 58.1%.Patients with positive carotid and coronary findings(n=89) occupied 73% of all.Patients with carotid intima-media or carotid artery plague had higher prevalence of coronary artery disease than those without carotid disease.The sensitivity and specificity of this finding is 95.7%and 50.7%respectively.Multivariate analysis revealed that age, blood pressure,plasma glucose,BMI(P<0.05) were predictors of coronary artery disease whereas only age and blood pressure(P<0.05)were predictors of carotid artery disease.Conclusion:Carotid intima-media thickness or carotid artery plague is a strong predictor of coronary artery disease.Only age and blood pressure were strong predictors of carotid artery disease.