Investigate The Prevalence Of High Myopia And High Myopia Associated With Chorioretinopathy Among Adults Aged 50 Or Above In Wuxi City

Objective High myopia and high myopia associated with chorioretinopathy are one cause of visual acuity impairment in an elderly population,there is currently no effective treatments. At present, high myopia and high myopia retinopathy epidemiology data is less in China’s older population especially in south of Jiangsu.To investigate the prevalence and risk factors of high myopia and high myopia associated with chorioretinopathy,observe visual acuity impairment in residents aged 50 years or over in Wuxi,China,and provide the basis for blindness blind.Methods Cluster sampling was used in randomly selecting individuals aged ≥50 years in 28 communities in Binhu District of Wuxi from June to December 2010. 6150 individuals received questionnaire and a comprehensive eye examination including visual acuity,refraction,slit-lamp microscopic examination and direct ophthalmoscopy and so on.Spherical equivalent(SE)was used to determine the degree of refractive errors.The diagnosis of high myopic chorioretinopathy was made if SE<一6.00 D and myopic chorioretinal atrophy lesions were presented such as posterior scleral staphyloma,lacquer cracks,Fuchs spot and myopic arc spots.The degree of visual acuity impairment was determined according to the World Health Organization(WHO) classification as low vision(the best corrected visual acuity≥0.05,but<0.3)or blindness(the best corrected visual acuity<0.05).Results There were 3.69 %(227/6150)high myopia patients, in which 71.37 %(162/227)patients were associated with myopic chorioretinopaty.The prevalence of high myopia in gender,high myopia family history,smoking,alcohol drinking is different(X2=6.40,136.99,4.99,13.74;P<0.05).Logistic regression analysis showed that there were significant differences in the prevalence of high myopia between people with family history( r=2.010, P<O. 05) and alcohol drinking( r=-0.798,P<O.05), the former is dangerous factor,the latter may be protective factor.There were 47 cases of bilateral blindness,201 cases of unilateral blindness,84 cases of bilateral low vision and 214 cases of unilateral low vision in those participants. In 162 cases of high myopic chorioretinopathy patients,77(47.53%)cases had an obvious visual impairment,including 6.38%(3 cases)of bilateral blindness,19.95%(20 cases)of unilateral blindness,19.05%(16 cases)of bilateral low vision and 17.76%(38 cases)of unilateral low vision.Conclusions The prevalence of high myopia of residents aged≥50 years in Wuxi,China is relatively high.Family history is the important risk factor and alcohol drinking may be the protective factor in high myopia patients. High myopia associated with chorioretinopathy and visual acuity impairment can not be ignored.