| Type 2 diabetes mellitus (T2DM) cognitive impairments are most frequently related to memory, which mainly contributed to abnormal glucose metabolism are found as a brain complication in T2DM. Currently neuroimage researches have detected brain damage directly in patients with T2DM:MRI brain scan has indicated that memory impairments are associated with atrophy of the global brain and hippocampal area in patients with T2DM. And diffusion tensor imaging (DTI) can detect its presence extensive abnormal white matter connections seen in further study. Functional imaging data has corroborates these findings, with functional magnetic resonance imaging (fMRI) suggesting reduced connectivity between the hippocampus and surrounding brain regions. Electroencephalogram (ECG) findings in patients with T2DM have revealed their longer stimulus signal reaction time, worse alertness and attention remarkable. These neuroimage studies help to further elucidate the mechanism of diabetic encephalopathy. |
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