The Follow Up Of Recent Quality Of Life In Very Low Birth Weight Infant

Objective:Analysis recent prognosis of VLB W and investigate possible high risk factors about the bad neurological outcomes to give them effective intervention and improve their quality of life to the greatest extent.Methods:The database of VLBW hospitalized between October,2013 and October,2014 was reviewed.Results:1. When discharged, the motality was 13.00% and treatment abandon rate was 17.39%. Cure rate and improved rate were 43.48%,26.13% respectively. Among the survival neonatal(N=200),when following up to corrected age 6 months, drop out rate was 6.50%. Motality was 27.00%, and 81.48%(44/54) were dead 1 week after discharged. The rate dead from gaving up or improving without healed because of or mainly because of economy was 74.07%(40/54).2. The physical growth of VLBW was obviously below normal at corrected age 1 month,3 months,6 months. The abnormal rate of weight was always smaller than height. Abnormal rate was gradually reduced with age rising.3. Among the cases done ophthalmoscopy, rates of retinopathy of prematurity(ROP) I and ROP II were 19.27% and 64.22% respectively.25 cases(89.29%) returned to reexamine until retina vascularization.3 cases(10.71%) refused to follow up and reexamine. Among the cases done brainsteam auditory evoked potential(BAEP) or transient evoked otoacoustic emission(TEOAE),5.10% did not pass in one ear and 11.22% did not pass in both ears.95 cases did Magnetic resonance imaging(MRI) examination, the presentation of intracranial hemorrhage and brain injury in premature infants were 10.53% and 9.47% respectively.4. The abnormal rate of neonatal behavioral neurological assessment(NBNA) done at corrected age 42 weeks was 100%. Among the cases done Gesell Developmental Scale, incidences rate of mild and moderate neurological lesions were 27.78% and 5.56% respectively at corrected age 3months. When we followed up to 6months, incidences rate of mild neurological lesions was 8.33% without incident of moderate neurological lesions. Vaginal blooding in pregnancy, gestational diabetes mellitus, mother’s education level, birth weight, gestational age, living environment(urban/rural), neonatal respiratory distress syndrome(NRDS), pulmonary hemorrhage, use of pulmonary surfactant(PS) and neonatal hypoglycemia had a significant effect on the neurodevelopment of VLBW at corrected age 3months (P<0.05); mother’s education level and age, gestational age, living environment (urban/rural), neonatal hypoglycemia and intracranial hemorrhage had a significant effect on the neurodevelopment of VLBW at corrected age 3-6 months (P<0.05)Conclusion:Economic condition is a significant factor that influences the survival and neurodevelopment of VLBW. There is a catch-up tendency in physical growth and neurodevelopment. Abnormal rates of ophthalmoscopy, hearing test and MRI are relatively low. Mother’s low education level and age≤24 years, diseases during pregnancy, treatments after birth, various complications especially respiratory tract diseases are high risk factors of neurodevelopment, which kind of children need follow up strictly.