A Study Of The Relationship Between Plasma Vitamin A Level And Viral Encephalitis In Children

Object:Through the study of plasma vitamin A concentrations in the acute and recovery phase of viral encephalitis in children and the connection in them by observing epidemiologic variables, clinic features, examinations, et al. The results will give a new idea and method for the clinical treatment and prevention of viral encephalitis.Methods:Collecting and analyzing the medical records of the hospitalized children in the Department of neurology in Children’s Hospital of Chongqing Medical University with 41 cases who have got viral encephalitis,25 cases with Tourette syndrome,32 cases with epilepsy and 33 cases of the healthy children from June to September in 2014. The plasma vitamin A concentration was measured by high performance liquid chromatography. All data was processed by SPSS. There were statistical differences when P<0.05.Results:1. The serum vitamin A levels in children with in the acute and recovery phase of viral encephalitis, Tourette syndrome, epilepsy and the healthy, were respectively 0.59±0.23umol/L,0.89±0.19umol/L,0.88±0.21umol/L, 0.85±0.15umol/L and 0.91±0.19umol/L. The mean plasma vitamin A concentration was significantly lower in the acute phase of children with viral encephalitis than those who were with Tourette syndrome, epilepsy and the healthy children (P<0.05), but no statistical difference found in the recovery phase(P>0.05).2. The mean plasma vitamin A concentrations were significantly higher in the recovery phase than in the acute phase of viral encephalitis in children (0.89±0.19umol/L vs 0.61±0.23umol/L, t=9.134, P<0.001).3. There was no statistical difference in the association between the plasma vitamin A concentrations in acute phase of viral encephalitis in children with epidemiologic variables, clinic characteristics, examinations, et al(P>0.05).Conclusion:Plasma vitamin A concentration significantly decreased in the acute phase of viral encephalitis, while it gradually increased along with the recovering. That is to say, the vitamin A level could get back to the normal level in a short period. There were no statistical differences between vitamin A deficiency and epidemiologic variables, clinic characteristics, examinations, et al.