Study On The Epidemiology Of Seasonal Conjunctivitis In Students Aged 6-13 Years In Yangpu District In Shanghai And The Treatment Of Integrated Traditional Chinese And Western Medicine

Background:Seasonal allergic conjunctivitis is a common chronic allergic disease in the population, which usually affects patients’ normal work and study. The incidence of the disease tends to increase, the onset age become younger, the risk factors tend to diversity. The epidemiological studies on the prevalence of seasonal conjunctivitis and its risk factors in Shanghai are still rare. In addition to conventional Western Medicine treatment (such as: 0.1% Olopatadine), many traditional Chinese medicine treatment has become a research hotpots. So, Combined the Department of education and traditional Chinese medicine, we study the epidemiology prevalence and risk factors of seasonal conjunctivitis and explore the role of Chinese medicine for its treatment.Objective1. Through this study, to obtain relevant data of the prevalence of regional SAC in Shanghai.2. By conventional western medicine and traditional Chinese medicine combined treatment, we aim to reduce the relapse, or shorten the course of disease, or to reduce the prevalence of severity and reduce the eye drops’ damage.3. To popularize the related knowledge of seasonal conjunctivitis for teachers and parents, to promote children developed good health habits, to promote social awareness and attention of the disease, and to improve health consciousness.Methods1. A total of 2200 students of 4 school were enrolled in this study by the whole group sampling method. Using the questionnaire survey, this study carried out accomplish with the regular students of the students’ census work.2. The positive children were divided into observation group and control group, 60 cases in observation group and 76 cases in control group. The observation group were treated with oral administration of traditional Chinese medicine’a wind scattered’ and 0.1% Olopatadine, while the students in control group were treated with 0.1% Olopatadine eye drops.3. According to the students’ subjective symptoms (table):itchy eyes, eye foreign body sensation, photophobia, lacrimation; slit lamp examination signs of change (table):conjunctival hyperemia, edema, and the secretions. The symptoms and signs of eye were observed at 3 days,1 weeks and 2 weeks after treatment, and the score was recorded, and the efficacy was determined after the treatment.Results1. A total of 2174 students who answered the questionnaire effectively from 4 schools were included in the study.136 pupils were diagnosed with seasonal conjunctivitis (including 28 cases diagnosed as severe cases), the prevalence of seasonal conjunctivitis was 6.3%.2. The history of seasonal conjunctivitis and allergic history, family history of allergic conjunctivitis, asthma, allergic conjunctivitis, family allergic conjunctivitis, myopia, and eye itch were related to the symptoms of the disease. In particular, our data showed that children grew up in families with the history of allergic conjunctivitis, had 3.578 times higher chance of getting SAC than those without family history. We also found that the odds of SAC significantly increased in the students with history of SAC (2.79 times). When analyzed the students with the symptom of eye itching or lacrimation, the change for SAC was as high as 6.5 times.3. After 2 weeks,112 patients were treated (observation group,64 cases,48 cases). The observation index of the two groups before treatment were compared, the results showed that the difference between the two groups was not statistically significant. One week after the treatment, the observation group compared with the control group, the ocular symptoms and total score was lower, the difference between the two groups no significant (P>0.05); after 2 weeks of treatment, observation group and the control group compared ocular symptoms and signs. The total score was lower, and the difference between the two groups was statistically significant (P<0.05).Conclusions1.The prevalence of seasonal conjunctivitis in primary school students in Yangpu District is 6.3%. Allergic history, family history, seasonal conjunctivitis, familial seasonal conjunctivitis were associated with the prevalence of seasonal conjunctivitis.2.For children with seasonal conjunctivitis, compare with the 0.1% Olopatadine,the integrated traditional Chinese and western medicine can better improve the ocular symptoms and signs, and get more curative effect.3. Through this study, promoted children developed good health habits and social awareness and attention of the disease.