Man Pen Kang Using Irrigation Treatment Of Chronic Pelvic Inflammation(Damp And Hot Accumulate Knot Poison And Blood Stasis Syndrome) Clinical Research

Objective:Compared with placebo further evaluation man pen kang using irrigation treatment of chronic pelvic inflammation (damp and hot accumulate knot poison and blood stasis syndrome) the safety and effectiveness, for its in the clinical application of scientific basis to provide a powerful.Methods:take randomized, double-blind,-placebo-controlled clinical trial, will meet the chronic pelvic inflammation (damp and hot accumulate knot poison and blood stasis syndrome diagnosis standard 64 patients divided into A group and B group, and the basin filling kang group slow intestinal fluid therapy, the B group choose a placebo (slow basin filling simulation using Cornwall agent) treatment, drug treatment for two menstrual cycles. 3-5 days after menstruation clean start medication, medication for 14 days for a cycle, continuous administration 2 menstrual cycle.The two groups each observed before and after treatment and related symptoms and signs integral curative effect and the safety index changes.Results:(1) in the two groups of the chronic pelvic inflammation and damp and hot accumulate knot zhuzheng curative effect of poison, the A group’s greater rate was 70%, the total effective rate was 100.00%; The B group’s greater rate was 0.00%, the total effective rate was 38.46%, the A group compared with B, a statistically significant (P< 0.05);(2) the total curative effect in the two groups compare:the A group’s greater rate was 60.00%, the total effective rate was 100.00%; The B group greater’s rate was 15.38%, the total effective rate was 46.15%, the A group compared with B, a statistically significant (P <0.05);(3) in the two groups of traditional Chinese medical syndrome compare the efficacy: the A group’s greater rate was 60.00%, the total effective rate was 97.50%; The B group’s greater rate was 7.69%, the total effective rate was 38.46%, the A group compared with B, a statistically significant (P< 0.05);(4) in two groups of local signs curative effect comparative:the A group’s greater rate was 57.5%, the total effective rate was 100.00%; The B group’s greater rate was 7.69%, the total effective rate was 53.85%, the A group compared with B, a statistically significant (P <0.05);(5) the security:this experiment, the experimental total adverse events appear 9 casees (11 times), of which appear in 10 times mild digestive system is unusual,2 cases with drug for sure,2 cases are likely to have relationship with drugs,6 cases may be associated with the drug,1 case of accidental pregnancy has nothing to do with drugs.The incidence was 16.98%, the clinical application security。Conclusion:man pen kang irrigation is using the honeysuckle, common cnidium fruit, dandelion, kindhearted yi ren, defeated sauce grass, wild chrysanthemum flowers, big blood cane, root, fumaric nine taste of Chinese traditional medicine. Has qingrejiedu, qushi adjustable gas, for activating blood circulation and eliminating stasis efficacy, used in the treatment of damp and hot accumulate knot poison stasis syndrome the chronic pelvic inflammation, can obviously improve the lower quadrant abdominal pain, pain and lumbar di ministry of color yellow gas down more smelly wait for a symptom, the greater rate and the total effective rate is better than a placebo, clinical use safety, convenient, is worth further promotion. In the process of test, only a small number of subjects have adverse reactions in the digestive system, and ease after drug ruled out, no serious adverse reactions, clinical use is safe.