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Analyzed On The Factors Associated With Type 2diabetes Mellitus And Glycemic Control In Gusu District

Posted on:2016-09-12Degree:MasterType:Thesis
Country:ChinaCandidate:Y Z GaoFull Text:PDF
GTID:2284330482460071Subject:Public health
Abstract/Summary:PDF Full Text Request
Objective:T o analyze the prevalence of type 2 diabetes mellitus(T2DM), the influence factors on the glycemic control state and the population structure of new patients detected in community screening.Methods:21 communities in Gusu district were randomly selected through multi-stage cluster random sampling method. The residents(≥18 years) lived in these21 communities more than 6 months were selected for the present study. After excluding the people with glucocorticoids drugs using, pancreatic disease, pregnancy,types 1 diabetes mellitus and the recent history of rubella virus infection, a total of12,585 people were included in this survey. The investigators were trained with uniformed questionnaire. The demographic information, risk factors of lifestyle,medical history and physical examination data were collected. According to the diagnostic criteria for T2 DM, the prevalence of T2 DM in Gusu district was calculated.The relationships between the risk factors and T2 DM and glycemic control were analyzed by multiple logistic models, respectively. The odds ratio(Odds ratio, OR)and 95% confidence intervals(95% Confident interval, 95% CI) were calculated with SPSS 17.0. In addition, demographic characteristics of the newly diagnosed T2 DM patients were analyzed by descriptive method.Results:1. The prevalence of T2 DM in Gusu district was 9.53%. The standardized prevalence rate was 6.54% and 5.97% according to the Jiangsu and national demographic data,respectively.2. Univariate analysis showed that aging(OR=14.47, 95%CI: 11.46-18.28), male (OR=1.15, 95%CI: 1.02-1.30), family history(OR=6.82, 95%CI: 6.01-7.74), smoking(OR=1.20, 95%CI: 1.05-1.37), obesity(OR=2.10, 95%CI: 1.74-2.54), abdominal obesity(OR=2.49, 95%CI: 2.20-2.82) were risk factors of T2 DM in Gusu district.3. By multiple logistic models, significant relationships were observed between T2 DM and aging(OR=1.67, 95%CI: 1.58-1.76), abdominal obesity(OR=1.44,95%CI: 1.23-1.69), obesity(OR=1.13, 95%CI: 1.02-1.26), family history of T2DM(OR=8.81, 95%CI: 7.49-10.40), hypertension(OR=2.36, 95%CI: 2.04-2.74) and hyperlipoidemia(OR=1.63, 95%CI: 1.33-1.99).4. The rate of poor glycemic control was 34.78%. The main factors affecting the glycemic control were waist circumference(OR=1.82, 95%CI: 1.27-2.63), physical activities(t=2.30, P=0.022), course of disease(t=-3.69, P=0.000) and treatment methods(χ2=9.84, P=0.002).5. 15.60%(187/1199) T2 DM patients were newly diagnosed in this study. Compared to the patients diagnosed before, they were often middle-aged, self-considered in good health, have not regular routine of physical examination, do not know location of the community health service institutions.6. Gusu district was divided into three regions named A, B and C. The prevalence of three regions was 10.03%, 8.94% and 9.37%, respectively. There was no statistically significant difference among of them(χ2=2.14, P=0.34). The top three risk factors of T2 DM in region A and C were family history of T2DM(OR=11.12, 95%CI:8.35-14.82), hypertension(OR=2.30, 95%CI: 1.79-2.30) and hyperlipoidemia(OR=1.66, 95%CI: 1.19-2.31). In region B, The top three risk factors of T2 DM were family history of T2DM(OR=10.07, 95%CI: 6.36-15.95), hypertension(OR=2.30,95%CI: 1.53-3.54) and abdominal obesity(OR=1.90, 95%CI: 1.22-2.95).Conclusion:1. The prevalence of T2 DM in Gusu district was lower than the national and provincial level. The family history of T2 DM, hypertension, hyperlipoidemia, obesity, abdominal obesity and aging were the risk factors of T2 DM for residents in Gusu district. Moreover, the result showed that abdominal obesity, physical activities,course of disease and treatment methods were the influence factors on glycemic control.2. There were 15.60% T2 DM patients were newly detected in this study.Strengthening health screening and propaganda about community health services should be implemented immediately.3. The risk factors associated with T2 DM and glycemic control were slightly different among 3 regions of Gusu district. Disease prevention and control work should be carried out based on the actual situation.
Keywords/Search Tags:Type 2 diabetes mellitus, risk factors, glycemic control, health screening
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