Endoscopic Submucosal Dissection For The Treatment Of Gastric Leiomyoma Originated Form The Muscularis Propria Layer

Objective : The aim of this study was to determine the feasibility of endoscopic submucosal dissection(ESD) for the removal of gastric leiomyoma from the muscularis propria layer and to evaluate the efficacy and safety of ESD for this indication.Methods:From July 2013 to June 2014, 19 cases of patients with gastric leiomyoma from the muscularis propria layer were examined by endoscopic ultrasonography(EUS)and CT in Yantai Yuhuanding Hospital,then treated with ESD after intubation anesthesia.The patients were followed up with gastrocope for evaluation of therapeutic effect and safety.Result:19 lesions were completely resected with ESD.Perforation occur in 1 case during the dissection of the lesion, which was successfully closed with metal endoclip without surgical treatment.19 lesions were confirmed gastric leiomyoma after pathological examination. The size of lesions ranged from 0.8 to 4.3cm with a mean resected size of 2.5cm. The mean ESD procedure time was 76.8min(range from 40 to150min).All parents had a little of blood loss during ESD.But none of them had other complications after ESD.Conclusion: ESD is an effection and safe endoscopic surgical procedure to resect gastric leiomyoma originated from the muscularis propria layer.