The Screening Evaluation Research For Family Close Contacts Of Hospitalized Tuberculosis Patients

ObjectiveSurvey hospitalized tuberculosis patients family close contacts of tuberculosis screening rate, infection rate and its influencing factors.Analyze the effects of different rates of PPD positive for family close contacts, and the sensitivity, specificity and accuracy.Methods1. In accordance with the method of continuous into the group selection in December 2012- December 2014 hospital treated 1045 cases of PTB patients,family close contacts as investigation object, a total of 3098 cases. 2. Design survey form of TB screening and infection factors associated with, and confirm the validity of qualified, by trained and qualified resident and the attending physician as investigators, to survey respondents. 3. Use PPD test screening, tuberculosis standards by the relevant results of 《tuberculosis diagnosis standard for diagnosis 》 of the ministry of health formulate in 2008,Respondents positive for PPD,given sputum smear, erythrocyte sedimentation rate, and X-ray examination, clinical manifestations diagnosis of tuberculosis infection. 4. Outcome measures:①Statistics in close contact with the patient’s family PTB TB screening rates, analysis of relevant factors screening rates; ② Statistical PTB in close contact with the patient’s family TB infection, analyze predisposing risk factors; ③Different PPD-positive results were observed in close contact with family and PPD TB infection rate sensitivity, specificity, and accuracy. 4.The data were first order, assignment, two categorical variables assigned by 0,1, more categorical variables dummy line processing, application of medical statistics package SPSS17.0 statistical correlation factor analysis using X2 analysis first, initial screening difference statistically significant factors, and then build multivariate Logistic regression analysis to obtain the value of each variable Wald X2, P value, OR values and their 95% CL values, P<0.05 was statistically significant.Results1, 1045 cases of patients with PTB family close contacts a total of 3098 cases, 2596 cases investigated and screened, the screening rate was 83.80%, among which 1279 were male, female 1317 cases, the average(39.11 + 29.22) years of age, not screened 502 cases, not the screening rate was 16.20%, among which 264 were male, female 238 cases, the average(40.06-29.82). Screened 2596 PTB patients family close contacts, 326 patients with positive TB infection, infection rate was 12.56%. 2, Age, place of residence, cultural level, family income, the popularity is TB prevention and control of PTB family close contacts the screening rate of the key factors(OR1=0.522,OR2=3.046,OR3=0.171,OR4=1.795,OR5=2.882,P<0.05). 5. Age, place of residence, cultural level, family income, the popularity and TB prevention and control of BCG vaccination status, mark, have a medical examination, early case, the results of the hospitalized patients with sputum smear, diabetes, smoking, excessive drinking, respiratory system diseases were the key factors influencing the PTB family close contacts infection rates(OR1= 4.668,OR2=4.668,OR3=0.974,OR4=3.795,OR5=4.784,OR6= 10.184,OR7=9.763,OR8=3.581,OR9=9.865,OR10=10.907,OR11=9.911,OR12=7.865,OR13=6.859,P<0.05). 4.PPD test negative, generally positive, strong positive PTB family group in close contact with TB infection rates were 0,32.17%, 71.57%, the higher the degree of positive PPD test, the higher TB infection, PPD sensitive laboratory diagnosis of TB infection degree, specificity and accuracy were 100%, 86.61%, 88.29%.Conclusion1.The family close contacts of The hospitalized PTB patients,TB screening rate is low, the infection rate is higher, need high attention. 2. Age, place of residence, cultural level, family income, the popularity of TB prevention and control were the key factors of PTB family close contacts screening rate, the need to strengthen the older age, low culture crowd, low family incomes of TB prevention knowledge education, to improve the rate of TB screening. 3. The young and old, rural population, low educational level, low family income, low popularity, no TB prevention and control of BCG vaccination, card mark negative, not early checkup, hospitalized patients with sputum smear positive TB in hospital infection patients’ families close contacts TB infection rate is higher, need to focus on strengthening the crowd TB infection monitoring. 4.PPD super positive performance, TB prevalence is high, the need for further examination.