Analysis Of Risk Factors Of Rebleeding Within Two Weeks After Endoscopic Treatment Of Esophageal And Gastric Variceal Bleeding

Objective: To analyze the risk factors of rebleeding within two weeks after endoscopic treatment of esophageal and gastric variceal bleeding,in order to provide evidence for preventing the recurrence of esophageal and gastric variceal bleeding effectively.Methods: This experiment enrolled 421 patients diagnosed as esophageal gastric varices bleeding.According to the presence of hemorrhage after endoscopic treatment,the patients were divided into bleeding group and no bleeding group.Then compared general conditions,lab examination,CTP classification, Blatchford grade,time of endoscopic, the degree of varices,number of ligations and so on in two groups.Finally,I obtained the risk factors affecting haemorrhage within two weeks after endoscopic treatmen by using single factor and multi-factor logistic regression analysis.Results: 1 、 75 percent of the EGVB patients were administrated emergency endoscopy and endoscopic hemostatic.The endoscopic bleeding control rate was92.6%,7.4% of the patients complained of hematemesis and/or melena after treatments.2、When compared the two groups in age,gender,history of diabetes,portal vein thrombosis, hypersplenism, the degree of varices, number of ligation, Blatchford grade, there were no statistical differences. Cr and PT prolonged,ALB decreased,the patients of CTP B and C were more when compared with not bleeding group,The above differences had statistical significance(p<0.05).3、The Regression coefficient of PT,CTP classification,endoscopic bleeding and ascites is positive,OR value was more than one,which were proved to be risk factors affecting rebleeding after endoscopic treatment. The Regression coefficient of ALB was negative, confirmed to be protective factors by single factor logistic regression analysis, above had statistical significance.4、Using multi-factor logistic regression analysis,PT, endoscopic bleeding and ascites were verified to be the independent risk factor.5、The 316 patients who took emergency endoscopy were further divided into bleeding group and no bleeding group.It turned out the scores of CTP and Blatchford were more,PT prolonged and rate of endoscopic bleeding was higher.there were statistical differences(p<0.05).Conclusion: 1 、 Emergency endoscopy and endoscopic hemostatic were administrated in most of the patients. The recurrent bleeding rate was low. the bleeding control rate was high.2、PT,CTP classification,endoscopic bleeding and ascites were proved to be risk factors.ALB was confirmed to be protective factors.what’s more,PT,endoscopic bleeding and ascites were verified to be the independent risk factor affecting hemorrhage after endoscopic treatment.3、 The recurrent bleeding of emergency endoscopy group was related to the amount of upper gastrointestinal haemorrhage were more,the poor liver function, poor blood coagulation function and endoscopic bleeding.