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The Clinical Analysis Of The Changes Of Liver Function And The Complications After Primary Liver Cancer Operation

Posted on:2016-03-21Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhouFull Text:PDF
GTID:2284330479492266Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: Observation of liver function in patients with primary liver cancer underwent surgical resection of HCC lesions after liver and complications, to evaluate the safety and efficacy, changes of liver function before and after surgery, and the preoperative grading of liver function and postoperative complications after Child relationship.Methods: Reasonable selection of Alexander hospital, Tumor Hospital of Shanxi Province in 2009 July to 2014 October, and consistent with the conditions of 60 cases of primary liver cancer patients were confirmed by pathology, complications, and all patients wererecorded before and after the operation in 3D, 7d, 15 d index of liver function,postoperative 7d appeared in the front the liver function and liver function Child 7d andpostoperative Child grading.Results: Postoperative 7d in patients with AST compared with the preoperative levels(14.81 ±9.44) U/L, ALT compared with preoperative levels(48.38 ± 25.36) U/L, AST, ALT(P < 0.05) before and after surgery were statistically significant, ALB value and operationtreatment after the operation than before the decline in the average value(8.73 ± 0.88)g/l, the ratio of plasma albumin in the human body(P < 0.05), before and after surgerywere statistically significant, DBIL levels than before treatment increased the averageoperation(4.84 ± 0.49) umol/L, IBIL levels than beforetreatment increased the averageoperation(3.36 ± 0.46) umol/L, DBIL, IBIL(P > 0.05) operation before and after the operation were not statistically significant. Postoperative 7d in patients with ASTcompared with the preoperative levels(73.48 ± 48.14) U/L, ALT compared with preoperative levels(60.69 ± 22.09) U/L, AST, ALT(P < 0.05) before and after surgerywere statistically significant, operation after treatment ALB levels were decreased inaverage(3.44 ± 1.95) g/l two, the differences were statistically significant(P < 0.05), the DBIL level was increased before treatment the average operation(2.14 ± 3.20) umol/L,IBIL levels than before treatment increased the average operation(2.78 ± 1.03) umol/L,DBIL, IBIL(P > 0.05) before and after surgery were not statistically significant. Patients received operation treatment of many complications after 7d, such as the liver surface projection area pain in 56 cases, postoperative body temperature is greater than 37.8 degree fever 56 cases, patients felt obvious abdominal distension and abdominal pain in 33 cases, 5 cases after eating nausea, vomiting in 2 cases, pleural effusion in 2cases, infection in 10 cases, 4 cases of intra-abdominal bleeding, gastrointestinal bleeding, 7 cases of biliary fistula in 5 cases, liver failure in 1 cases of abdominal cavity.Preoperative liver function of patients given Child grade of liver function, a liver functionin 52 cases, B grade 8 cases, postoperative liver function grade A in 43 cases, liver function B grade 17 cases. Patients 7 days after surgery complications exceptabdominal distension, abdominal effusion, gastrointestinal bleeding, intra-abdominal bleeding, abdominal infection, liver failure in different preoperative Child gradedifference was statistically significant(P < 0.05), the difference was not statistically significant(P > 0.05).Conclusions: Surgical treatment of primary liver cancer is safe and effective for patients with effective and accurate assessment of liver function before operation, reasonable medication is very important. In patients with primary liver cancer and underwent surgery after there will be a lot of complications, at the presentstage of primary liver cancer underwent open resection after preoperative complications was mainly fever, abdominal distension,nausea, vomiting, liver pain etc.. The liver function of patients with Child B level before operation, operation after treatment more prone to bloating, abdominal effusion,gastrointestinal bleeding, intra-abdominal bleeding, abdominal infection, liver failure. In view of such a situation may occur after surgery, preoperative improvement of liver function, improve liver reserve ability, in order to reduce the postoperative complications, improve surgical treatment of primary liver cancer, effectiveness, safety,rationality...
Keywords/Search Tags:Primary liver cancer after operation complications, Child-Pugh classification of liver function, hepatocellular carcinoma, liver function
PDF Full Text Request
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