The Cerebral Function Monitoring And Prediction Of Prognosis With The Electroneurophysiology In Severe Cerebrovascular Disease

Objective : To investigate the value of electroencephalography, somatosensory evoked potential, brainstem auditory evoked potential and transcranial doppler ultrasound on the evaluation of cerebral function of patients with severe cerebrovascular disease. To find out the ways that can predict the cerebral function prognosis of patients with severe cerebrovascular disease objectively and accurately.Methods:In 24 hours after admitted to hospital, the patients with severe cerebrovascular disease were examined by electroencephalography, somatosensory evoked potential, brainstem auditory evoked potential and transcranial doppler ultrasound. The prognosis of cerebral function were evaluated 3 months after the onset of severe cerebrovascular disease or when the patients died in 3 months. Analyze the relationships between the results of the exams above and cerebral function prognosis. Find out the ways that can predict the cerebral function prognosis of patients with severe cerebrovascular disease objectively and accurately. Compare the new ways and traditional Glasgow Coma Scale in sensibility, specificity and veracity of prognosis prediction to find out whether the new ways are better than traditional Glasgow Coma Scale.Results:Ordinal logistic regression analysis found that electroencephalography(P=0.023), somatosensory evoked potential(P < 0.001) and brainstem auditory evoked potential(P=0.019) have a significant effect on the prediction of cerebral function prognosis of severe cerebrovascular disease patients. The sensibility, specificity and veracity of the new ways for the prognosis prediction are 84.7%, 85.7% and 85.0%. While the Glasgow Coma Scale’s are 65.2%, 78.6% and 68.3%. χ2 analysis found that the differences between the new ways and traditional Glasgow Coma Scale in sensibility(χ2=4.696, P=0.030) and veracity(χ2=4.658, P=0.011) have statistically significant. The new ways are better than traditional Glasgow Coma Scale in sensibility and veracity of prognosis prediction. The difference between the new ways and traditional Glasgow Coma Scale in specificity( χ2=0.243, P=0.678) has no statistically significant. The new ways don’timprove the specificity of prognosis prediction.Conclusions : By using electroencephalography, somatosensory evoked potential and brainstem auditory evoked potential exams can make a prediction of prognosis of severe cerebrovascular disease patients objectively and accurately. As well as the new ways improve the sensibility and veracity of prognosis prediction. This is of great importance in evaluating the illness, predicting prognosis, diagnosing and treating severe cerebrovascular disease.