| The elasticity of vascular wall is an important characteristic of the maintenance of normal physiological function of vascular. In this thesis, the elastic characteristics of the radial artery wall are studied based on optical coherence tomography. First of all, the elasticity of radial artery wall was measured based on excitation source of heart beat, which was reflected as pulse waves in the radial artery. The elastic graph of vascular wall and the surrounding things were measured. Displacement of each point in the optical coherence elastic image was estimated by two-dimensional cross-correlation algorithm. The strain was estimated with the axial displacement map and transverse displacement radial artery map which were obtained by imaging of vascular based on the wavelet transform. Then, the strain map was obtained. Then the tissue modulus distribution map and Poisson’s ratio distribution map were depicted through the displacement map and strain diagram. The results show that OCE can detect the location and the shape of blood vessel effectively. This method is promising used in many applications.Multi-dimensional pulse wave velocity is an important indicator to evaluate the physiological conditions such as the vascular wall elasticity characteristics. Multi-dimensional pulse wave was detected by optical coherence tomography system. Firstly, the characterization of heart motion in the radial artery was measured, in other word, Mai Bobo. The pulse wave, i.e., the physiological signal, was denoised based on the wavelet transform. After that a three-dimensional pulse wave was constructed. Measurement method of three-dimensional pulse wave velocity was also researched. |
