Yiqiwenyang Treatments For Heart Failure Disease Xinshenyangxu Deficiency Syndrome Clinical Curative Effect Of Meta Analysis

Objective:Excavation profit yiqiwenyang theory of traditional Chinese medicine method of treatment for heart failure, applies the method of evidence-based medicine system evaluation of yiqiwenyang method for the treatment of chronic heart failure clinical research literature analysis, with the aid of inheritance of traditional Chinese medicine auxiliary system analysis, drug induced heart failure rule, reveals formula law, which will provide a scientific basis for Chinese medicine treatment of heart failure and new ideas.Methods:1. Collect all previous dynasties in the important subject that medical books and modern medical books related to heart kidney Yang deficiency, heart disease, according to the ancient, modern comb the development origin, induction heart kidney Yang deficiency type of heart disease and pathogenesis, syndrome and syndromes, combing heart kidney Yang deficiency in chronic heart failure disease pathogenesis and syndrome- "the formulas of knowledge;2. Through the electronic retrieval and manual retrieval, retrieval has been published in domestic medical journals in the past 20 years of good temperature Yang method of kidney Yang deficiency syndrome in patients with chronic heart failure heart randomized controlled or half randomized controlled clinical trials, according to the Cochrane systematic review method recommended by the manual assessment included in the study of risk of bias, using RevMan5.2 software for multiple research results the overall effect of Meta- analysis, inverted funnel chart analysis; With the inheritance of traditional Chinese medicine auxiliary system for heart failure clinical screening, the formula of the input, the formulas with the aid of statistical analysis of data analysis system mining laws.Results:1. The traces the origin of the doctrine of kidney Yang deficiency in chronic heart failure heart evolution, combed the pathogenesis syndrome- agent system, for clinically beneficial temperature Yang method is used to provide a theoretical basis for the treatment of chronic heart failure disease support, provide evidence-based medicine.2. The system evaluation were incorporated into 16 randomized controlled clinical trial, a total of 1244 patients, the risk of bias assessment shows its research methodological quality is low. Meta- analysis of cardiac function in improving curative effect evaluation of combined effect of RR(Risk thewire) and 95% CI: 1.20 [1.13, 1.27]; Improve the curative effect evaluation of combined effect of RR syndromes(Risk thewire) and 95% CI for the RR = 1.20(1.10, 1.31); Ejection fraction to improve curative effect evaluation of combined effects of MD(Mean Difference) and 95% CI: MD = 6.38(5.26, 7.50); Left ventricular end-diastolic diameter to improve curative effect evaluation of combined effects of MD(Mean Difference) and 95% CI: MD = 3.70(4.71, 2.69); By TCM traditional auxiliary system platform(V2.5) prescriptions for clinical heart failure analysis, determines the frequency of drug, the drug of correlation and composition, drugs, New Zealand, revealing the drug laws.Conclusion:This research review of chronic heart failure heart the origin and development of kidney Yang deficiency syndrome, comb "pathogenesis syndrome- agent" knowledge system, the system evaluation good temperature Yang method for the treatment of chronic heart failure clinical curative effect of kidney Yang deficiency syndrome, safety analysis, statistical analysis of prescription of clinical literature, draw the traditional Chinese medicine(TCM) syndrome network diagram, drug core combination, evolved to treat heart disease, New Zealand, build a medicine syndrome differentiation system, to benefit the temperature Yang syndromes in patients with chronic heart failure heart kidney Yang deficiency syndrome provides a scientific basis, to provide basis for clinical guidance to choose medicine syndrome differentiation.