This topic by intraperitoneal injection of SD rat Pentetrazole(PTZ) epilepsy model is set up,behavioral observation then epilepsy with Chaishaopingxiantang for intervention treatment,by Western blot detection Cav1.2 expressed in hippocampus ELISA method to detect brain GABA content,and study its mechanism Collection of 30 cases of children with epilepsy as the research object,analyzes its before and after treatment,research,to verify the clinical curative effect,in order to provide the basis for clinical treatment of epilepsy and the instruction Epilepsy by experiment Chaishaopingxiantang convulsions grades,onset duration of epilepsy rats,GABA content reduced in the brain tissue,the excessive expression of Cav1.2 have therapeutic effect.Chaishaopingxiantang in clinical treatment effects of children with epilepsy,by experimental and clinical study speculated that the mechanism may be related to improve the content of GABA in brain tissue,reduce the expression of the hippocampus Cav1.2. |