| Objective: Malignant body-surface metastasis developed to a certain extent. There will be ulceration, pain and other symptoms. The effect of repeated treatment for advanced disease is poor. The research on the basis of chemotherapy combined Cinobufacini element injection local injections for advanced malignant body-surface metastases treatment, observation of chemotherapy in combination with local injections of traditional Chinese medicine external treatment to treat malignant body-surface metastasis tumor of the clinical curative effect.Methods: This study is still in the early stages of clinical research. The sample is 10 patients with malignant body-surface metastases to the clinical diagnosis of malignant skin, giving Cinobufacini injection locally injected. At the same time according to different parts of the tumor with reference to the NCCN guidelines. We choose the appropriate chemotherapy regimens to systemic chemotherapy by comparing before and after surface treatment lump size, color, nature, improve pain,ulcer healing, such as compression symptoms change.Results: By observing the ampoule Cinobufacini element local injections of joint and systemic chemotherapy to treat malignant body-surface metastasis of 10 patients with metastases, tumors disappeared,1 case remised completely and body surface ulcers completely healed; The double diameter measurement mass of the six patients has narrowed by 50%; The double diameter measuring mass of three patients has narrow by less than 50%.The total effective rate is 70%.The stability factor rate is 100%. Seepage, local pain, pressure symptoms have significantly improved.Conclusion: Cinobufacini element injection injected locally by combining systemic chemotherapy have the significant effect to treat malignant skin metastases,to relieve local pain, to reduce exudation, to lighten the pressure symptoms and to improve patients’ quality of life,. It is one of the most safe and effective methods to treat the malignant skin metastases. |
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