Rudimen Analysis Of Connectivity Changes In Migraine′s Disease With The Type Of Feng-huo In Resting State

Object:Imageology study has shown that the brain structure and function in patients with migraine of feng-huo type have changed. This study used the characteristic of spontaneous neuronal activity in patients with migraine of feng-huo type to discuss resting state functional magnetic resonance imaging technology.The research also analyzed the change of migraine resting state brain functional connectivity.It can give us a better understanding of the pathogenesis of migraine of feng-huo type.Methods: Incorparate 30 patients with migraine of feng-huo type,and also choose 30 healthy persons.They have the same age,gender, and education level. Compare the differences among them.Let them make resting state fMRI scan. Then use ReHo analysis and functional connectivity analysis to analyze the two kinds of methods of data processing: ①ReHo analysis: Through analyzing the differences of the two tested groups of ReHo in different brain regions to find out the different brain regions.Then use REST1.8 single sample and two sample T test to find differences in brain areas.② FC analysis:Select differences in brain regions of local consistency analysis as the seed point,analyze the seed point and the whole brain function connectivity.Compare the differences between the groups of groups of subjects of various areas of the brain functional connectivity,and test the results of two sample t.Results:1 The differences between migraine are in brain regions of ReHo for left cerebellum,left frontal straight back, right frontal lobe, right outside the dorsolateral frontal gyrus, the left edge of the leaf.2 Compared with healthy controls, the region of interest and whole brain functional connectivity show that the functional connectivity of migraine patients with gout condition of heat left cerebellum and left superior temporal gyrus, left inferior parietal lobule, right insula decreased functional connectivity(P < 0.05);the functional connectivity of the left orbital lobes straight back and right fusiform gyrus has decreased(P < 0.05);the function of the right frontal lobe; outer connected with the right cerebellum, left superior frontal gyrus weaken.The functional connectivity of the frontal orbital region, right premotor area has increased(P < 0.05); The functional connectivity of the right dorsolateral frontal gyrus and left precentral gyrus has decreased, connected with the foot back function enhancement of the right inferior temporal gyrus, the lower(P < 0.05). The left edge of the leaf and whole brain functional connectivity are without difference.Conclusion: The patients with migraine of feng-huo type headache interval function appear abnormal brain regions. The pathogenesis of these findings contribute to the understanding of migraine of feng-huo type.