| ObjectiveThrough the analysis of the clinical characteristics of subjects, medical history, family history, colonoscopy results and living tissue disease inspection found that the colon tumor occurrence and elated factors analysis, which will provide a scientific basis for improvement of colorectal cancer prevention and treatment.MethodsWere retrospectively analyzed between December 2012 and May 2013 in Kunming medical university first affiliated digestive endoscopy room accept electronic colonoscopy patients, patients’ information collection, registration each colonoscopy in patients with gender, age, height, weight, occupation, smoking history, drinking history, history of gallbladder excision, first-degree relatives of bowel cancer history and life history of adverse events in the past 20 years, the history of endoscopic check; According to the evaluation standard to record each colonoscopy inspectors colonoscopy can see, found the part of the polyp, histologic type, and the intestinal cleanliness, for each patient end to place the information such as the mirror, and establish relevant database.633 patients according to the unified standard colonoscopy were divided into normal group, adenomatous polyps, adenomatous polyps and colorectal cancer group, analysis of gender, age, height, weight, occupation, smoking history, drinking history, history of gallbladder excision, history of first-degree relatives of bowel cancer, living in the past 20 years history of adverse events between the groups of difference and relevance to colon cancer. Second adenomatous polyp group alone, adenomatous polyps and colorectal cancer group as the research object, analysis, the lesion site before colonoscopy examination results, etc. and colon cancer.Results1. Patients in 633 cases (male 305, female 328) colonoscopy in the normal group,481 cases (male 216, female 265);The adenomatous polyp group 39 cases (23 cases of male, female 16 cases);Adenomatous polyp group 79 cases (45 cases of male, female 34 cases);Colorectal cancer group of 34 cases (male 21 cases,13 cases), gender differences are significant (P=0.032).2. Of 633 cases of a.< 30 years old in 49 cases,30-112 cases,39 years old,40-177 cases,49,50 to 59,154 cases,106 cases of 60-69 years old,70-79-year-old 30 cases,> 80 years,4 cases.In 481 patients with normal group< 30 years old,46 cases 30-39 98 cases,40-137 cases,49,50 to 59,113 cases,65 cases of 60-69 years old, 70-79-year-old 22 cases,>80 0 cases;The adenomatous polyp group 39 cases,< 30 years old in 1 case,30-39,3 cases,14 cases of 40 to 49,50 to 59,13 cases,6 cases of 60-69 years old,1 case of 70-79 years old,> 80 years old in 1 case;Adenomatous polyp group 79 examples,< 30 years old in 1 case,30-39,7 cases,22 cases of 40 to 49,50 to 59 years old 20 cases,60-69-year-old 24 cases,4 cases of 70-79 years old, > 80 0 cases;34 cases of colorectal cancer group< 30 years old in 1 case,30-39,4 cases,4 cases of 40-49,50 to 59,8 cases,11 cases of 60-69 years old,70-79 years old in 3,> 80 years old in 3 patients.Age difference is significant (P< 0.001).3. BMI sentences is thin in 633 cases of client 53 cases,398 cases of normal, overweight 54 cases,117 cases of obesity,11 cases severe obesity;In normal group, 481 cases of angular 44 cases,333 cases of normal, overweight,8 cases of obesity in 86 cases,10 cases of severe obesity;The adenomatous polyp group of 39 cases of thin 3 cases,17 were normal,9 cases, being overweight obesity in 9 cases, severe obesity in 1 case;Adenomatous polyp group of 79 cases was thin 4 cases, normal 29 cases,28 cases of overweight, obesity,28 cases of severe obesity 0 cases;Group of 34 cases of colorectal cancer was thin in 2 cases,19 cases normal,9 cases, being overweight and obesity in 4 cases, severe obesity 0 cases;There are significant difference in body mass index (P< 0.001).4.633 subjects of freelance 143,118 farmers, workers,144 cases,106 cases of civil servants,45 cases in business, teachers in 49 cases,14 cases of students, medical 14 cases;Free profession in the normal group,481 cases of 116 cases,77 farmers, workers in 114 cases,79 cases of civil servants,39 cases in business, and teachers, the students 13 cases,12 cases of health care;The adenomatous polyp group 39 cases of professional idleness in 7 cases, farmers have 9 cases, workers in 14 cases, civil servants in 25 cases, doing business in 5 cases, teachers have 15 cases, students have in 1 case, health care has 2 cases;Adenomatous polyp group 79 cases is idle in 20 cases,20 cases of farmers, workers have 9 cases, civil servants in 16 cases, doing business in 2 cases, teachers have 9 cases, students have in 1 case, health care has 2 cases;Colorectal cancer group of 34 cases of freelance 0 cases,12 cases of farmers, workers in 16 cases,2 cases of civil servants, doing business in 1 case, teachers in 3,0 cases, students care 0 cases;Professional composition of significant difference (P< 0.001).5.633 subjects in 159 cases of smoking;Smoking in normal group,481 cases of 108 cases;The adenomatous polyp group of 13 cases of 39 cases with a history of smoking, no smoking history 26 cases;Adenomatous polyp group of 26 cases of,79 cases with a history of smoking without smoking history of 53 cases;Colorectal cancer group of 34 cases of 12 cases of smoking;Smokers constitute than there was no significant difference (P=0.054).6. A total of 633 patients with a history of drinking 106 cases,527 cases without history of alcohol;A total of 481 cases of normal group, has a history of alcohol in 78 cases,403 cases without history of alcohol;Polyps group 118 examples, has a history of drinking 22 cases, there is no history of alcohol in 96 cases;Group of 34 cases of bowel cancer, has a history of drinking 6 cases,28 cases there is no history of alcohol;7. History of patients,633 cases of gallbladder excision in 41 cases;Normal group, 481 cases of gallbladder excision in the history of 31 cases;In the adenomatous polyp group 39 cases,1 case history of gallbladder excision;Adenomatous polyp group,79 cases of gallbladder excision in the history of 5 cases;History of colorectal cancer group of 34 cases of gall bladder resection in 4 cases;There was no significant difference between groups (P= 0.456).8.633 cases of client level of family history of colorectal cancer in 47 cases;In normal group,481 cases of primary family history of colorectal cancer in 42;The adenomatous polyp group 39 cases of primary family history of colorectal cancer 0 cases;Adenomatous polyp history of first-degree relatives in the group of 79 cases of colorectal cancer (3 cases);Group of 34 cases of primary colorectal cancer family history of colorectal cancer in 2 cases;There was no significant difference between groups (P=0.114).9. Nearly two decades in 633 cases of client has a history of bad living habits,299 cases;Normal group was 481 cases,481 cases of;In 39 cases of adenomatous polyp group life history of 22 cases of adverse events in the recent 20 years, there is no life in the recent 20 years history of 17 cases of adverse events;Adenomatous polyp group of 79 cases of adverse events of life in the recent 20 years history of 42 cases, there is no life in the recent 20 years history of 37 cases of adverse events.Colorectal cancer group of 34 cases with 21 cases;There was no significant difference between groups (P=0.08).10. Colonoscopy in 633 cases of client out of a total of 152 cases of pathological changes, which is located in the left half colon 101 cases,30 cases of right half colon all 21 cases of colon;The adenomatous polyp group 39 cases located in the left half colon 27 cases, right-side colon 9 cases,3 cases of colon;Adenomatous polyp group with 79 cases in 45 cases located in the left half colon, right-side colon in 16 cases, all 18 cases of colon;Colorectal cancer group with 34 cases in the left half colon 29 cases, right half colon in 5 cases,0 cases of colon;Lesion location have significant difference between the distribution of groups, colonoscopy out lesions in left colon (66%) (P= 0.007).11. First colonoscopy in 152 cases of polyps or bowel cancer patients 107 cases, secondary inspection 35 cases, three times or more inspection 7 cases;In 39 cases of adenomatous polyp group 30 cases of first line endoscopic check second check 6 cases, three times or more to check 3 cases;First line group,79 cases of adenomatous polyp endoscopic check 47 cases,28 cases secondary inspection, check three times or more than 4 cases;34 cases of colorectal cancer in patients with primary check 30 cases,4 cases were secondary inspection, check three times or more than 0 cases;There are significant difference between groups (P=0.011).Conclusion1. Large intestine cancer men more than women,60-69 people aged more than other age groups, BMI exceeds bid is rare.Male adults in appropriate sports, reasonable meals, keep a good figure seems good.Colon tumor in farmers, workers, teachers, mechanism remains to be studied.2. Cases of various types of colon polyps in left colon, prompt a colonoscopy, left half colon should focus on observation.3. Colon tumor colonoscopy screening has high rate of missed diagnosis and misdiagnosis, prompt follow guidelines, increase the number of high-risk population screening and improve the level of endoscopy diagnosed necessary and urgent. |
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