Interventional Effect Of Glucomannan On Postprandial Blood Glucose Between Healthy Adults And Type 2 Diabetic Patients

Object: The dominant component of konjac is glucomannan, a kind of alkaline food which is rich in dietary fiber and various amino acids and microelements. Recent research shows that glucomannan contained in konjac has benefits in lowering the blood sugar levels of diabetics for the reason that it is of high molar weight and high viscidity which can effectively lower blood-sugar-levels. Moreover, glucomannan, with its powerful water absorptivity and low calories, can increase satiation, lighten the sense of hunger, and make the patients lose weigh; as a result, it is also an ideal choice for diabetics and people who want to lose weight alike.The current project aims to study the features of the dietary-fiber-rich glucomannan which is conveniently available in daily life and provide scientific evidence of diet treatment for diabetics.Method: In this study, 26 healthy adults and 30 type 2 Diabetic patients were selected to take normal cake(50g carbohydrates) or KGM cake(50g carbohydrates, 5% KGM) respectively. The blood glucose response were examed by at 15 min, 30 min, 45 min, 60 min, 90 min, and 120 min.The experimental results are all analyzed by using SPSS 12.0 statistical package.Results: The values of blood-glucose raised at 30 min, 45 min, 60 min and 90 min after intake of 50 g carbohydrates of normal cake between healthy adults and type 2 Diabetic patients, respectively. Meanwhile type 2 Diabetic patients owed a high level of blood-glucose and longer duration. KGM cake obviously decreased blood-glucose in comparison with normal cake, more clearly in type 2 Diabetics.Conclusion: Glucomannan, a soluble fiber derived from Amorphophallus konjac appears to beneficially affect glucose concentrations especially for type 2 diabetics than healthy adults. Glucomannan is thought to prolong gastric emptying time, which increases satiety, decreases the ingestion of foods, reduces the postprandial rise in plasma glucose, and also be effective in maintaining weight, which is of significance for precaution of diabetics and Metabolism Syndromes.