| Purpose To explore the effect of postoperative progressive resistance training in the upper limb function, quality of life and post-traumatic growth in breast cancer patients, and the security in the clinical application. Then provide scientific and effective method for breast cancer patients recover as soon as possible.Methods This study was a clinical randomized controlled trial. From March 2014 to January2015, we selected 66 patients in the first affiliated hospital of Dalian medical university who diagnosed with breast cancer and will have modified radical mastectomy and chemotherapy in this hospital. Participants were randomly divided into intervention group or control group, and there were 33 patients in each group. From 4 to 6 weeks postoperative and patients admitted to hospital for their first chemotherapy, intervention group patients would began a total of 12 weeks, 3-5 times/week, 2-3 sets/time progressive resistance training. The training form combined under supervision exercise during chemotherapy period in hospital and home-based exercise after chemotherapy.Control group patients did the routine training. In addition, all patients received a same content of health education. In order to improve the intervention compliance, patients in the intervention group need record exercise diary after exercise and received a follow-up call every week during home-based exercise period.Grip strength and shoulder joint activity(maximum rang of abduction, flexion, and extension) were evaluated respectively at 1 day before operation, 4 to 6 weeks after operation and the patients admitted to hospital for their first chemotherapy and after 12 weeks the patients admitted to hospital for their fifth chemotherapy. Lymphedema were assessed at 1 day before operation and every time a chemotherapy regimen(a course ofchemotherapy is 3 weeks) through measured double upper arm circumference. Quality of life(FACT- B, V4.0) and post-traumatic growth(PTGI) were assessment at the first and fifth chemotherapy.Results1. Patients suffering from upper grip strength(P = 0.005), shoulder joint abduction range(P = 0.006) and flexion range(P = 0.003) appear significant different trends follow time between intervention group and control group. After the intervention, patients suffering from upper grip strength, shoulder joint abduction range and flexion range in the intervention group were better than the control group.2. After the intervention, total score of quality of life in the intervention group were higher than the control group(P =0.001). The quality of life score in physical well-being(P=0.032), social/family well-being dimension(P = 0.001), emotional well-being dimension(P = 0.002) and additional concern dimension(P = 0.004) in intervention group patients were significantly higher than the control group.3. After the intervention, score of post-traumatic growth in the intervention group were higher than the control group(P=0.025). The post-traumatic growth score in relating to others(P = 0.030) and new possibilities dimension(P = 0.011) in intervention group were significantly higher than the control group.4. Both groups had no patients with lymphedema during the study period. The lymphedema incidence was 0%.Conclusion1. This study confirmed that progressive resistance training can effectively promote the suffering side upper limb physiological function and improve the function of upper limbs in breast cancer patients.2. The progressive resistance training can improve the quality of life and post-traumatic growth level in patients with breast cancer.3. The progressive resistance training for breast cancer patients is safe and feasible, will not cause adverse reaction such as lymphedema. |
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