The 29 Cases Of Clinical Characteristics And Risk Factors Analysis Of Lung Cancer Combined With Pulmonary Embolism

Objective: Pulmonary embolism is one of the severe complications in patients with lung cancer,it is mainly due to pulmonary artery or its branch blocked by endogenous or exogenous embolus。With pulmonary embolism in patients with lung cancer treatment will not only increase the difficulty, but also can lead to these patients survival time shortened and the decline in the quality of life, thus caused wide attention of clinicians,and became the hot spot of research in recent years。This study was to summarize and analysis of lung cancer complicating pulmonary embolism in patients with clinical manifestations and susceptible factors, enhance the understanding of the disease, do early diagnosis and treatment, so as to improve the prognosis of patients。Method: Collected from January 2009- January 2015 clinical data of 29 cases with pulmonary embolism in patients with lung cancer as case group, and apply a method of stratified sampling with 29 cases of patients with lung cancer information collected as control group。 Analysis and summary the 29 cases of lung cancer with pulmonary embolism in patients with clinical manifestations and imaging features, and on the basis of merging the two groups of patients disease, pathological types of lung cancer, and treatment for the statistical analysis, laboratory examination results, etc.RESULT: This research group income in 29 cases of lung cancer patients with pulmonary embolism group activities after paroxysmal dyspnea in 16 cases(55.2%), 6 cases of heart rate(20.7%), cough and expectoration in 10 cases(34.48%), 5 cases(17.2%)of chest pain, hemoptysis in 3 patients(10.34%), limb pain in 3 patients(10.3%), disturbance of consciousness in 1 case(3.4%). Within three months after the diagnosis of lung cancer,and the diagnosis of pulmonary embolism in patients in 17 cases(58.6%), 8 cases of patients 3 to 6 months, accounted for 27.6%, 6 and 12 months for 3 cases of patients, accounted for 10.3%;Have 1 case in more than 1 year, accounting for 3.4%.Two groups of patients with pathological types of lung cancer with 15 patients with pulmonary embolism in pathological types adenocarcinoma, accounted for 51.7%, 5 cases of squamous cell carcinomas, accounted for 17.2%, 3 cases of small cell lung cancer, accounting for 10.3%, 12 cases of lung cancer patients with pathological types of adenocarcinoma, accounted for 41.4%, 8 cases of squamous cell carcinomas, accounted for 27.6%, 5 cases of small cell lung cancer, accounting for 17.2%. Lung cancer with pulmonary embolism group III- IV in 26 cases, accounting for 89.66%, I- II(3 cases),(10.34%), 10 cases of I- phase II in lung cancer group, accounting for 34.48%, III- IV(19 cases), accounting for 65.52%. Lung cancer patients with pulmonary embolism group merged basic diseases, a total of 20 cases(68.97%), a total of 12 cases with basic disease in lung cancer group, accounting for 41.38%;Malignant tumor metastasis in lung cancer with pulmonary embolism group, 17 cases(58.62%), 23 cases of malignant tumor metastasis in lung cancer group, accounting for 79.3%. Has a history of chemotherapy in lung cancer with pulmonary embolism group of 27 cases, accounted for 93.1%, 3 cases of surgery, accounted for 10.34%, has a history of chemotherapy in lung cancer group 21 cases, accounted for 72.4%, 10 cases of surgery, accounting for 34.5%. Two groups of patients in age, sex, lung pathology classification, surgical treatment, PLT, Hb, WBC, Fib aspects carries on the statistical analysis showed there was no statistically significant difference between the two(p is greater than 0.05), and chemotherapy, combination of basic diseases, lung cancer staging, D- dimer, APTT and PT analyzed statistical significant differences(p isless than or equal to 0.05).CONCLUSION: 1.Lung cancer is one of the risk factors of pulmonary embolism, especially within three months after the diagnosis of lung cancer patients are more likely to appear the pulmonary embolism;With basic diseases, chemotherapy, terminal cancer are also the important risk factores for lung cancer patients with pulmonary embolism.2.Lung cancer patients with pulmonary embolism clinical manifestations of diversity, especially when the lung cancer patients with unexplained dyspnea should be more vigilant with pulmonary embolism may;D- dimer markedly increase closely related with the occurrence of pulmonary embolism.