Analysis Of The Imaging Characteristics Of Patients With Cardiac Amyloidosis

ObjectiveThis study was devised to retrospectively analysis and evaluate the imaging characteristics of cardiac amyloidosis and the important role of MRI and echocardiography played in its diagnosis, to further improve the diagnostic level.MethodsA total of5patients’imaging information was retrospectively analyzed,including echocardiogram and late gadolinium enhancement(LGE) cardiac magnetic resonance (CMR),the result of Congo red staining and the involvement extracardiac organs with their pathological findings was recorded.ResultsThese5patients were confirmed by the extracardiac tissue pathology biopsy for amyloidosis,4cases of renal biopsy,1case of tongue biopsy, Congo red staining were all positive;Echocardiogram showed left ventricular wall thickening generally, especially ventricular septal,ventricular diastolic limited,partial atrial enlargement(2cases),left ventricular ejection fraction partially injuried(2cases);In the LGE-CMR, global subendocardial LGE was present in4cases,locally transmural when it was seriously,additional, suboptimal myocardial nulling without discrete hyperenhancement. was found in1case.ConclusionsEchocardiography can identify the characteristics of cardiac amyloidosis,such as myocardial hypertrophy,atrial enlargement and the limition of ventricular filling,has good initial diagnostic value to its, but in the absence of a characteristic myocardial echogenicity and interatrial septum thickening.it can be easily misdiagnosed. Myocardial hypertrophy along with myocardial signal increasing in the sequence of Triple IR prompts to the diagnosis of cardiac amyloidosis,late gadolinium enhancement MRI can provide more powerful information for cardiac amyloidosis diagnosis and differential diagnosis.