Associations Of Anxiety And Depression During Pregnancy With Gestational Weight Gain

Objective:To describe the prevalence rate of prenatal anxiety and depression, and to explore the effect of degree and change of anxiety and depression during each trimester on gestational weight gain.Methods:Pregnant women who took prenatal care in a maternal and child health hospital in Zhejiang Province were invited to participate in our study. Well conducted self-made questionnaire was used to collect information about social demography, reproductive history, physical condition, life behavior and anxiety and depression at12th,28th and36th gestational week. Self Rating Anxiety Scale (SAS) and Self Rating Depression Scale (SDS) were used to assess degree of anxiety and depression, respectively. Information about delivery and neonates were also collected. Prevalence rates of prenatal anxiety and depression in each trimester were conducted. The association of degree and change of anxiety and depression during each trimester with gestational weight gain was analyzed by using multiple linear regression. Multinomial logistic regression was used to analyze the relation between prenatal anxiety/depression change and insufficient/excessive gestation weight gain. Combined effects of prenatal anxiety and prenatal depression were also analyzed. Results:1. Finally2156,1493and1286pregnant women participated in our study in1st,2nd, and3rd trimesters, respectively. Among those,969pregnant women participated in all three trimesters. The prevalence rates of anxiety and depression during1st,2nd, and3rd trimesters were14.3%,8.3%,11.7%and50.9%,35.4%,36.0%, respectively. SAS and SDS scores were44.33±8.47,42.67±7.64,43.41±8.05and49.84±9.74,46.21±9.47,46.44±9.89in1st,2nd, and3rd trimesters, respectively, which were all higher than those of Chinese norm.2. SAS scores in2nd and3rd trimesters were positively related with increased BMI in whole gestation (P=0.02, P=0.0242; P=0.02, P=0.0164); SDS scores in1st trimester were negatively related with increased BMI in1st trimester (P=-0.01, P=0.0184).3. Anxiety in3rd trimester only, in both1st and2nd trimesters, and in any trimesters might associated with excessive gestational weight gain (OR=2.32,95%CI,1.15-4.69; OR=4.55,95%CI,1.30-16.02; OR=1.73,95%CI,1.19-2.53). Anxiety in2nd and3rd trimester, either or both, might all related with excessive gestational weight gain (OR=2.40,95%CI,1.13-5.08; OR=2.03,95%CI,1.24-3.32; OR=2.00,95%CI,1.09-3.65; OR=1.91,95%CI,1.22-3.00). Associations of prenatal depression with gestational weight gain were not observed.4. Combined effects of prenatal anxiety and prenatal depression were not observed.Conclusion:1. The prevalence rates of anxiety and depression during pregnancy are high.2. Prenatal anxiety, especially in2nd and3rd trimesters, may be related with excessive gestational weight gain. Interventions of gestational mental hygiene should be taken to improve maternal and fetal health.