Study On Reflux Esophagitis Correlation With Body Mass Index Risk Factors

Objective: Explore correlation between Body Mass Index (BMI) and RefluxEsophagitis (RE)， and correlation between RE and Gender，nationality differences， riskfactors of RE. Analyze the result to understand the influence of BMI on occurrence of RE.and also ethnicity,, gender, age,, gender differences are considered. BMI’s role in theoccurrence of RE as well as practical work to prevent and provide a theoretical basis fordiagnosis and treatment of RE. Method: Selected353patients for endoscopic test todetermine reflux esophagitis, take RE patients as observe group, others as controlgroup,measure height, weight to calculate body mass index, test blood pressure, Fastingplasma glucose,total cholesterol and Triglycerides, record smoking and drinking history.Results:①According to BMI, patients were divided into normal (18.5<=BMI <24);overweight(24<=BMI <28); obesity(28<=BMI). Occurrence and severity RE havesignificant correlations with BMI（χ2=49.581,P=0.001）, which is statistically significant.Severe RE（B class and above）grading ladder with（7.8％，45.3％，47.1％） BMIincrease(normal，overweight，obesity), Indicateing that higher BMI result in higher risk ofRE.②S moking（OR=1.838，P=0.035）, Age（OR=2.425，P=0.001）, high blood pressure（OR=2.529，P=0.028）, and obesity（OR=5.065，P=0.007） are risk factors of RE.Conclusion;①H igher BMI increases occurrence and severity of RE.②Smoking, Age（every15years elder）, high blood pressure, and obesity can increase RE risk for1.838，2.425，2.529，5.065times.③Gender, ethnicity do not affect occurrenceof RE, fastingplasma glucose, total cholesterol and triglycerides, drinking have no significancerelevance on RE.