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The Study Of Cardiovascular Complications In Chronic Kidney Disease Patients With Renal Anemia And Hypersensitive C-Reactive Protein

Posted on:2015-07-02Degree:MasterType:Thesis
Country:ChinaCandidate:J L HeFull Text:PDF
GTID:2284330467960153Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Objective To investigate the prevalence of cardiovascular complications in chronic kidney disease and its relationship with renal anemia and hypersensitive c-reactive protein.Method The data of942in-patients with renal anemia in our hospital from March2010to July2013were collected and retrospectively analyzed.Results1, In the942patients with renal anemia, the percentage of CKD patients in1-5stage CKD was1.70%(16cases),4.46%(42cases),118.47%(74cases),16.42%(153cases),59.13%(557cases). The hemoglobin (Hb) level in1-5stage CKD was100.13±11.45g/L,99.21±13.34g/L,98.88±11.65g/L,91.53±13.90g/L,78.94±18.02g/L.2, The prevalence of coronary artery disease (CAD), left ventricular hypertrophy (LVH), congestive heart failure (CHF), cerebral vascular accident (CVA), large atheromatous disease (LAD) in patients with CKD in stage1-5was31.25%,54.76%,58.05%,60.78%,65.88%, and the prevalence of CAD, LVH, CHF were increased (P<0.01). but no statistically significant effect on CVA, LAD.3, Anemia can be divided into mild, moderate, severe three groups. As anemia is aggravating, the prevalence of CAD, LVH increased (P<0.01), while the prevalence of CHF, CVA and LAD no statistical difference (P>0.05).4, According to the hs-CRP levels are divided into low-risk group (hs-CRP<1.0mg/L), medium risk group (1.0mg/L^hs-CRP≤3.0mg/L), the high risk group (hs-CRP>3.0mg/L), the prevalence of CAD, LVH, CHF, CVA and LAD was statistically difference (P<0.05).Conclusions1. The prevalence of low hemoglobin, cardiovascular disease is increased with the decline of renal function.2. Decline of renal function increase the prevalence of CAD, LVH, CHF, but no statistically significant effect on CVA, LAD.3. Anemia can increase the prevalence of CAD, LVH.4. hs-CRP can increased the prevalence of cardiovascular complications (CAD, LVH, CHF, CVA, LAD).
Keywords/Search Tags:Chronic kidney disease, renal anemia, C-reactive protein, Cardiovascular disease
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