Kidney Detoxification Of TCM Clinical Research For The Treatment Of Light Of Of Systemic Lupus Erythematosus

Objective:This research through clinical observation of kidney detoxificationmedicine in combination with small dose of glucocorticoid therapy light sle (systemiclupus erythematosus) to assess kidney detoxification medicine for light kidney empty cardof poison accumulate the clinical efficacy of systemic lupus erythematosus.Methods：Random, positive drug control methods will be incorporated into thestandard light of systemic lupus erythematosus (sle) patients were divided into treatmentgroup and control group, experimental group,34cases in the control group of34cases,patients with kidney detoxification medicine in combination with small dose ofcorticosteroids and hydroxychloroquine treatment, control group using small doses ofcorticosteroids joint hydroxychloroquine treatment, observation period for12weeks.Observe and record the treatment of patients with0,4,8,12weeks of ESR, CRP,WBC, Hb, PLT,24h urine protein quantitative, complement (C3and C4) effect ofresistance and breathing, blood pressure, pulse, temperature, electrocardiogram (ecg), liverfunction, renal function, blood routine, urine routine, stool routine safety indexes suchas;Observe and record the treatment of0,4,8,12weeks in patients with lumbar debility,fever, dizziness, tinnitus, macula, limb pain, loss of hair, skin ulcers, GanYan dry mouth,be agitated, night sweats, blurred vision, menoxenia symptoms and syndromes of TCM,such as the integral;Observe and record0,4,8,12weeks in patients with dosage ofprednisone and total amount;Observe and record the treatment of patients with a0,12weeks of antinuclear antibodies (ANA) and double-stranded DNA antibodies (ds)-DNAantibody resistance indexes such as antibody, and SLEDAI score;Research and analysis oflight of systemic lupus erythematosus (sle) kidney kidney detoxification medicineaccumulate the clinical curative effect, hormone use, and the case of adverse reactions and processing.Results:Disease, curative effect evaluation:12weeks after treatment, the treatmentgroup,34cases of clinical ease in5cases,14cases were markedly effective, effective in11cases,4cases were invalid, the total effective rate was88.24%;Clinical ease in2cases,control group of34cases,9cases had marked effect,12cases were effectively, invalid in11cases, total effective rate was67.65%.After statistics analysis, the differences betweenthe two groups was statistically significant (P0.05), the experimental group is better thanthe control group.Syndrome curative effect analysis:12weeks after treatment, treatmentgroup34cases, alleviate clinical in5cases,16cases had marked effect,10cases wereeffective,3had no effect, the total effective rate was91.18%;Clinical ease in2cases,control group of34cases,9cases had marked effect, effectively and13cases,10cases ofinvalid, the total effective rate was70.59%.After statistics analysis, the differencesbetween the two groups was statistically significant (P0.05), the experimental group isbetter than the control group.TCM symptoms comparison: in lumbar debility, fever,dizziness, tinnitus, macula, limb pain, loss of hair, skin ulcers, GanYan dry mouth, beagitated, night sweats, blurred vision, menstruation to be not moved, etc., are statisticallysignificant differences (P0.05), the test group were better than control group in improvingthe symptoms, especially in the physical pain, irritability, etc.Effect in laboratory index, therelated antibody laboratory index and SLEDAI score and total dosage of prednisone anddifferences were statistically significant (P0.05), the treatment group were superior tocontrol group, in such aspects as the ESR, Hb, urine protein quantitative is particularlyprominent.Conclusion：Kidney detoxification medicine in combination with small dose ofcorticosteroids and hydroxychloroquine light treatment kidney empty toxic aggregates,systemic lupus erythematosus (sle) in disease curative effect and syndrome curative effect,the main symptoms and signs, laboratory index, etc., are better than with small dose ofglucocorticoid hydroxychloroquine.Light with kidney empty poison accumulate thepathogenesis of systemic lupus erythematosus (sle), kidney detoxification is the effectivetreatment.Studies show that kidney detoxification medicine in the treatment of kidneyempty light systemic lupus erythematosus (sle) poison accumulate card safe and effective.