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The Effects Of Myocardial Oxygen Consumption、Bloodrheology、 Cardiac Function Of NXkkFY Ⅱ On Coronary Atrery Disease

Posted on:2016-05-09Degree:MasterType:Thesis
Country:ChinaCandidate:C Y LiuFull Text:PDF
GTID:2284330467498956Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Coronary heart disease incidence is the pathophysiological basis ofatherosclerotic lesions in the coronary arteries, based on the lipid bloodvessel wall, vascular occlusion, myocardial oxygen supply and oxygen demand imbalances, myocardial ischemia caused by lack of oxygen, the myocardial needed oxygen and other materials are in short supply and metabolites to remove obstacles and accumulation, lead to all kinds of the occurrence of coronary heart disease (CHD). Especially to cause cardiac insufficiency patients with lower quality of life, and even cause life-threateningacute myocardial infarction. High blood viscosity is the basis of coronaryatherosclerosis and thrombosis causes, and the serious influence of myocardial perfusion, myocardial ischemia caused by lack of oxygen, metabolicdisorders; And the degree of myocardial ischemia and the weight of thesymptoms is mainly composed of how many decision of myocardial oxygen consumption, the current clinical traditional western medicine treatmentis mainly to reduce myocardial oxygen consumption (representative drugs:beta-blockers betaloc), improve the coronary blood flow (representative drugs: such as nitric acid lipid drug isosorbide mononitrate), inhibition of platelet aggregation (representative drugs: the enteric aspirin), Mentor profes sor yu-xiang dong to the motherland medicine theory of Yin and YangWu-Hsing six-channel pattern identification, From the pathogenesis of coronary heart disease (CHD) with qi deficiency and blood stasis, phlegm turbidity, and so on, at the same time, using a lot of traditional Chinese medicine blood adhesion, improve the characteristics of blood oxygen metabolism, select remove stasis phlegm, qi and invigorating qi, such as compatibility of drugs into NXKKFYâ…¡, oral liquid, his own should can delay the onset of coronary heart disease complications effectively, reduce highblood sticky state, and on the improvement of the myocardial diastolic function have better effect. The main purpose of this study is the number of NXKKFYâ…¡ clinical experimental application of the oral liquid, by observing the clinical indicators of myocardial oxygen consumption in heart rate and systolic blood pressure, blood rheology, brain natriuretic peptide changes, every index study through NXKKFYâ…¡ number oral liquid on myocardial oxygen consumption, myocardial diastolic function, blood viscosity,the effects of all kinds of complications to reduce myocardial infarctionand heart failure, at the same time, provide data support for clinical use.This experiment in patients with coronary heart disease can be dividedinto5groups, each group of30people, respectively, control group1(betaloc), control group2(isosorbide mononitrate), control group3(entericaspirin), and NXKKFY â…¡ low-dose group, the conventional dose group.Each group of patients with oral drugs for15days, the comparison group, control group2,1NXKKFY â…¡ low-dose group, the conventional dosegroup to detect the heart rate and systolic blood pressure before treatment,brain natriuretic peptide, liver, kidney function, drug use during the day1(before treatment),3,7,11,16days before the morning heart rate, systolic blood pressure, and draw the heart rate x value changes in systolic blood pressure curve, compare three groups (enteric aspirin), and NXKKFYâ…¡ low-dose group, the conventional dose group test, liver and kidney function, blood rheology indexes before and after treatment at the same time to track side effects, drug side effects, along with the symptoms and complications of coronary heart disease symptoms. Experimental results show that the NXKKFYâ…¡ number two groups compared with control group,control group21oxygen while no significant difference (P>0.05), andcompare three groups with NXKKFYâ…¡ often.Coronary heart disease (CHD) in ancient Chinese medicine known as the obstruction, the medical scientist zhang zhongjing in on "fame Yin string" summarized the obstruction of the characteristics of the heartache of this virtual to real, TCM believes that this virtual to jun fire fire, gas liftabnormal of liver wood was the main reason for the coronary heart disease, the resulting haemorrheological nature, and qi stagnation, phlegm turbidity and blood stasis pathologic basis. Treatment should be removing yourfire to cure, at the same time line, cold gas, polyester phlegm and blood.NXKKFYâ…¡, oral liquid, according to clinical syndrome differentiation of traditional Chinese medicine theory to select a variety of remove cold phlegm stasis, sun Microsystems material, activate blood, can adjust the monarch drug compatibility to the fire and into, studies his own reduce myocardial oxygen consumption, improve blood viscosity and cardiac function,alleviate symptoms of coronary heart disease, reduce the complications and the effect that the occurrence of myocardial infarction (ami). To sum up, through the experiment we can get the following conclusion: the NXKKFYâ…¡ number oral liquid cardiac insufficiency in patients with coronaryheart disease and cause the cause of myocardial oxygen consumption, coronary heart disease have better adjustment for blood viscosity.
Keywords/Search Tags:NXKKFYâ…¡, myocardial oxygen consumption hemorheology, bloodviscosityaaa, brain natriuretic peptide (BNP), blood viscidity
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