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Evaluate Pre-PCI And Post-PCI Left Ventricular Rotation And Twist Motion Of The Patients With ST-segment ElevationMyocardial Infarction Through Three-dimensional Speckle Tracking Echocardiography

Posted on:2016-08-31Degree:MasterType:Thesis
Country:ChinaCandidate:G LiFull Text:PDF
GTID:2284330467497125Subject:Clinical Medicine
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Objective:Apply3-dimensional speckle tracking Echocardiography (3D-STE)to observe pre-PCI and post-PCI left ventricular rotation and twistmotion of the patients with the ST-segment elevation myocardialinfarction, and discuss the left ventricle systolic function and post-PCIcurative effect of these patients.Material and method:Carry out ultrasonic cardiogram check on30patients of FirstHospital of Jilin University with ST-segmentation elevation acutecoronary syndrome before PCI operation,7days,3months and6months after the operation respectively. For30age-matched patientsregarded as the normal control group, collect all-capacity3D dynamicimage storage of the left ventricle with apical four-chamber viewthrough the chest, and apply built-in3DT analysis software for off-lineanalysis, and then obtain the peak apical rotation of each segment andthe whole of the left ventricle (Prot-base, Prot-mid, Prot-ap,Prot-glo),the whole peak twist of the left ventricle (Ptwi-glo), the twist angle time to the peak of each segment and the whole of the left ventricle (TimePtwi-base, Time Ptwi-mid, Time Ptwi-ap, Time Ptwi-glo), and comparethe difference among all parameters of the patients with ST-segmentelevation myocardial infarction before and after PCI in different time.Result:The patients with ST-segment elevation myocardial infarctionshowed different left ventricular rotation, twist curve form, anddeformation trend before and after PCI. The form and deformation trendafter operation at different time were approximately the same. With theextension of the time, the myocardium recovery status was obvious.Compared with the normal control group, the left ventricularrotation and the twist angle of the patient group before the operation,7days,3months and6months after the operation were reduced. The twistangle time to the peak was extended. The significant difference beforethe operation,7days,3months and6months after the operation hasstatistical significance (P<0.05). The difference of6months after theoperation does not have statistical significance (P>0.05).With regard to the comparison between the pre-operation andpost-operation, the left ventricular rotation and twist angle beforeoperation,3months and6months after the operation were increased.The twist angle time to the peak was shortened. Such significantdifference has statistical significance (P<0.05). The difference of7days after the operation does not have the statistical significance (P>0.05).With the extension of the time, the post-operation rotation and twistangle were increased, and the twit angle time to the peak was graduallyshortened.Through the comparison of7days,3months, and7months afterthe operation, the left ventricular rotation and twist angle were increased,and the twist angle time to the peak was shortened. The difference hasstatistical significance (P<0.05).Conclusion:The left ventricular rotation and twisting motion of the patientswith the ST-segment elevation myocardial infarction were seriouslydamaged. After PCI, the recovery was not obvious in short term. Withthe extension of the microcirculation and reperfusion time, theimprovement was especially significant.3D-STE can accuratelyevaluate the abnormality of pre-PCI and post-PCI left ventricularrotation and twisting motion of the patients with ST-segment elevationmyocardial infarction, and then it can evaluate the left ventricularsystolic function.
Keywords/Search Tags:ultrasound speckle tracking imaging, 3D, rotation, twist, leftventricle
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