The Relationship Between Hyperlipaemia And Gestational Hypertension Disease

Objective: To explore the normal pregnant women, mild preeclampsia,severe preeclampsia patients blood lipid metabolism. Understand the abnormallipid levels increased with gestational hypertension disease.Methods: A total of96patients with gestational hypertension disease, itcan be divided into2groups:32cases of mild preeclampsia,64cases of severepreeclampsia patients. Another choose72cases of pregnancy with internal andsurgical diseases such as normal pregnant women as control group. Correct age,gestational age, and other conditions affecting the blood lipid metabolism,detection of serum total cholesterol (CHOL), triglyceride (TRIG), high-densitylipoprotein (HDL-C), low density lipoprotein (LDL)-c), apolipoprotein A1(APOA), apolipoprotein B (APOB) were compared.Results: Patients with gestational hypertension disease blood TRIG, LDL-C and CHOL, APOB compared with the control group had significant difference(p0.05) or less. Scope of lipid levels in mild preeclampsia patients: CHOL:4.18+/-2.24, TRIG:5.94+/-1.47, LDL:2.94+/-1.00, APOB:123.25+/-45.21.The scope of lipid levels in severe preeclampsia patients: CHOL:5.26+/-2.04, TRIG:7.32+/-2.10, LDL:3.54+/-1.30, APOB:156.58+/-66.79. WithTRIG, CHOL, sensitivity is higher.Conclusion: In this paper, the data shows, in patients with gestationalhypertension disease blood TRIG, CHOL, LDL-C level with the aggravation ofrise, and significantly higher than normal pregnant women (P<0.05or0.01), theresults are statistically significant, and the TRIG, CHOL, sensitivity is higher.HDL-C, no significant change (P>0.05). Prove the existence of patients withgestational hypertension disease, lipid metabolism disorders and as the illness isaggravating, a significant increase trend, lipid metabolism disorders and reportsthe results of the foreign scholars. At present in obese people, simply by the dietto prevent gestational hypertension disease, there is still no consensus, but cancontrol weight, aerobic exercise, thereby reducing the blood triglycerides,insulin, blood sugar concentration and alleviate the sympathetic nerves, andincreases the concentration of HDL-C, increase insulin sensitivity. Andcholesterol-lowering drugs such as pravastatin could improve vascular lesions inpatients with gestational hypertension disease, still need more experimentalstudy.