| Objective:The purpose of this paper is to study the effects of recurrent ovarian cancer patientschoose different treatment on the quality of survival, and analysis of the influence of otherfactors of quality of life for patients with recurrent ovarian cancer, individualized treatment,and provide reference for improving the quality of life.Method:(1) Subjects: collected in October2010-October2014admitted to the clinical data ofpatients with recurrent ovarian cancer Second Hospital of Jilin University, in strict accordancewith the inclusion criteria,80cases were collected, which accepts a secondary tumorreduction32patients resection combined with chemotherapy,48cases of patients with simplechemotherapy.(2) Research contents: using self-made core volume general situation questionnaire andthe European Organisation for research and treatment of cancer of the table EORTCQLQ-C30(V3.0) questionnaire Chinese version of the quality of life of patients withrecurrent ovarian cancer.(3) Statistical methods: the data of this paper uses SPSS21.0analysis software, usingP<0.05as the difference was statistically significant. Comparison of categorical variablesusing chi square test; the grade variable data using rank sum test; clinical indicators in thisstudy after test of normality of continuous variables, obey the normal distribution, usingindependent samples T test; do not obey the normal distribution, the rank sum testindependent samples test. Correlation analysis of linear correlation between age and thechoice of various clinical parameters.Selection rank correlation analysis and correlation ofrelapse frequency analysis of various clinical parameters. Comparison of the two groups werechosen survival Kaplan-meier survival analysis. Results:(1) Recurrent ovarian cancer using secondary cytoreductive surgery+chemotherapypatients physical function, role function and function scores were significantly higher thanthose in the field of chemotherapy; emotional function, cognitive function, no significantdifference in the functional areas of society.(2) The quality of life in patients with recurrent ovarian cancer affected by many factors.Age and frequency of recurrence and functional areas score was negatively correlated withtumor stage in patients with higher scores early in functional areas, better quality of life.CA125in patients with normal physical function, role function, social function scores weresignificantly higher than in patients with elevated CA125in patients in complete remissionafter treatment, the functional areas scored higher than partial remission, patients with stabledisease and disease progression.(3) Univariate analysis showed that older, more the number of recurrence, tumor stagelate, go turn the situation worse disease, the worse the quality of life of patients. Multivariateregression analysis showed that age, illness has returned turn out to predict the role offunctional areas; return transfer disease, CA125values have predictive symptom score;different treatment options for the overall health of score could predict.Conclusion:Patients with recurrent ovarian cancer using two cytoreductive quality for survival+chemotherapy group was higher than that of simple chemotherapy group. Patients withrecurrent ovarian cancer can prolong survival time and improve the quality of survival afterrecurrence by selectively accept secondary cytoreductive surgery+chemotherapy. Quality oflife in patients with recurrent ovarian cancer is influenced by many factors, the physicianshould select individualized treatment plan for the patient and master the best timing oftreatment, and to take an active interventions to improve survival and quality of life inpatients with recurrent ovarian cancer. |
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