Research On Diagnosis And Treatment Of Diabetes Mellitus With Dyslipidemia Under The Combination Of Disease And Syndrome Based On The Structured TCM Hospital Records

Objective:Through the "diabetes collection system structure of TCM hospital medical records" in the medical record data in data mining, to Discuss combination of disease and syndrome of traditional Chinese medicine diagnosis and treatment law to Type2Diabetes Mellitus With Dyslipidemia,so as to extruds the characteristics and advantage of traditional Chinese medicine, provide effective agent and train of thought for clinical treatments.Method:1.Data source:from "diabetes collection system structure of traditional Chinese medicine hospital medical records" in China academy of traditional Chinese medicine hospital of Guang’anmen endocrinologist from2004to2011Type2Diabetes Mellitus With Dyslipidemia’s medical records of2249cases, extract into standard data of1072cases of medical records, divided into several information table, according to the current national standards, industry standards for man-machine combination of normalize finishing.2.Data mining methods:(1) using SPSS19.0descriptive statistics, statistical analysis software for general data than the qualitative data to frequency, composition expression. The multi-target joint statistical classification by frequency conversion for crosstab method.(2) With reference to relevant standards, inductive Type2Diabetes Mellitus With Dyslipidemia evidence type decision rules, quartering disease of the all cases data in accordance with the card type decision rules, adopt computer discrimination and the method of man-machine combination analysis to determine the Type2Diabetes Mellitus With Dyslipidemia.(3)Joint analysis using multiple indexes at all levels of disease commonly used TCM frequency, using Clementine association rules in data mining platform, the commonly used single herbs and medicine, three ingredients, four herbs compatibility and clinical commonly used compound, summarize the medication rule of Chinese traditional medicine.(4) By the method of multi-index joint analysis condition commonly used prescription frequency at all levels, summed up the formula using law of each phase of each card type.(5) Based on the regression analysis method,research the "card-indicators" relationship.(6)Using Clementine data mining platform of the bayesian network analysis, study the syndrome and symptoms, formula, the relationship between the physical and chemical indicators, Type2Diabetes Mellitus With Dyslipidemia of summary and induction therapy and combined disease.Result:1. The whole crowd analysis.By analysis of data mining on the whole crowd: Blood rise975cases (90.9%),> age50,801cases (74.7%), BMI overweight797cases (74.3%), abnormal blood lipid index,761cases (71.2%), type2diabetes duration>5years732cases (68.3%) and hypertension694cases (64.7%). Has a history of smoking male289cases, has a history of drinking218cases of men. Gender had a greater influence on the history of smoking and drinking. Illness tongue analysis at all levels, the top three, respectively is dark red tongue (39.9%),(27.7%), light dark red tongue tongue (17.2%). Moss as the analysis of the top three, respectively is thin white moss (31.2%), thin yellow moss (19.6%), white greasy moss (17.7%). Pulse condition analysis of the top three, respectively is a heavy fine veins (26.2%), and is fine veins (16.4%), and strings (14.6%).2. The certificate-index analysis of the relationship:Early qi and Yin deficiency and blood stasis syndromes associated with triglyceride; Yin deficiency syndrome is associated with low density lipoprotein hotness; Mid-term deficiency of blood stasis and fasting plasma glucose, triglyceride and low density lipoprotein; Qi and Yin deficiency wet phlegm syndrome associated with low density lipoprotein; In the late two empty wet phlegm, blood stasis, Yin and Yang is associated with low density lipoprotein, triglyceride, total cholesterol.3. Find diagnosis rule combined disease:According to the course of type2diabetes mellitus,it can be divided into early, middle and late3period. Each period is divided into three card. Early disease common performance:blood lipid disorders with elevated triglycerides, low density lipoprotein rise is given priority to, the parting was IV type; Often accompanied by family history of high blood pressure and high blood pressure. For the highest percentage of qi and Yin deficiency and blood stasis (20%), primary symptom of fatigue, shortness of breath, drink more, sweating, dizziness, blurred vision, night to urinate, dark red tongue, moss thin white, pulse string, prescriptions are danshenyin,shengmaisan,liuwei dihuang tang. Followed by Yin deficiency heat syndrome (14.4%), primary symptom of dry mouth, drink more, urinate frequency, blurred vision, stay, chest tightness, shortness of breath, fatigue, frequent urination, night sweating, red tongue, less moss, pulse string.prescriptions are yunvjian,zhibaidihuangtang. Then to qi and Yin deficiency syndrome (9.4%), primary symptom to dry mouth, drink more, fatigue, insomnia, numbness, blurred vision, sweating, urination and frequency, light and dark tongue, moss thin white, pulse heavy fine prescriptions are shengmaisan,liuweidihuangtang. Single Chinese medicine herbs in radix rehmanniae, radix ophiopogonis, fructus schisandrae, rhizoma anemarrhenae, radix scrophulariae, pinellia, rhizoma atractylodis, twotooth achyranthes root, rhizoma coptidis, radix puerariae. Medium condition common performance:dyslipidemia with elevated triglycerides, low density lipoprotein rise is given priority to, the parting was IV type, often accompanied by family history of high blood pressure and high blood pressure, and merge with an increase in coronary heart disease, cerebral infarction and other vascular lesions. Master card for qi deficiency and blood stasis syndrome (19.5%), the symptom with dizziness, limb weakness, numbness, pain, blurred vision, sweating, urination and frequency, fatigue, dry mouth, frequent urination, night tongue reddish, moss thin white, pulse heavy fine. Prescriptions are siwutang,danshenyin,dangguibuxuetang subtraction. Followed by qi and Yin deficiency and dampness phlegm syndrome (8%), symptoms to stay, abdominal distension, palpitations, body pain, dry mouth, dizziness, frequency of urine, light and dark tongue, white greasy moss, pulse string is given priority to. Prescriptions are erchentang,huopuxialingtang,wulingsan.Then the qi and Yin deficiency syndrome (8%), dry mouth, with symptoms more drink, fatigue, palpitations, dizziness, night to urinate, stay, abdominal distension and numbness, blurred vision, bosom frowsty, tongue reddish, moss thin white, pulse fine to give priority to. Prescriptions are liuwei dihuang decoction, shengmaisan. Single Chinese medicine herbs in salvia miltiorrhiza, cortex moutan, yam, amomum villosum, coix seed, pseudostellaria root, astragalus root, etc of invigorate the circulation of qi qushi, Chinese traditional medicine for drug salvia miltiorrhiza+radix rehmanniae, radix astragali and radix rehmanniae, radix astragali+salvia miltiorrhiza is given priority to, such as three ingredients and four herbs to dogwood, alisma and poria cocos++radix rehmanniae radix rehmanniae, paeonia suffruticosa+dogwood, poria cocos, cortex moutan+dogwood, alisma+poria cocos, cortex moutan, rhizoma alismatis, poria cocos and radix rehmanniae. Late in the common performance:dyslipidemia in total cholesterol, low density lipoprotein, elevated triglycerides. low density lipoprotein rise is given priority to, parting with a and b Ⅱ Ⅱ,Ⅳ type. Accompanied by diabetes, high blood pressure history, family history of high blood pressure, diabetes, coronary heart disease history, diabetes history of cerebral infarction. Lord of Yang deficiency and blood stasis syndrome (25.9%), symptoms in body pain, chest pain, limb weakness, numbness, chest tightness, shortness of breath, fatigue, palpitations. Light and dark tongue, moss thin white, pulse heavy fine. Prescriptions are dangguishaoyaosan, huangqi guizhi wuwu tang subtraction. Followed by Yin and Yang deficiency syndrome (7.4%), dry mouth with symptoms, heart palpitations, shortness of breath, limb edema, body pain, physical activity, numbness, urination, sweat. Tongue reddish, moss thin white, pulse string is fine to give priority to. Prescriptions are liuwei dihuang soup, jinkuishenqisoup,shipiyin. Then for two empty wet phlegm and blood stasis, Yin and Yang (6.9%), dizziness, with symptoms stay, palpitations, drink more, blurred vision, body pain, night to urinate, dry mouth. Light and dark tongue, white greasy moss, pulse string is given priority to. Prescriptions are wulingsan,huopuxialingtang. Single Chinese medicine herbs in poria cocos, salvia miltiorrhiza, angelica, radix paeoniae rubra and rhizoma chuanxiong, radix astragali, radix pseudostellariae, atractylodes, radix paeoniae alba, yiqi huoxue, water, such as traditional Chinese medicine is given priority to, for medicine poria cocos+radix rehmanniae, radix angelicae sinensis and radix rehmanniae, radix ophiopogonis+salvia miltiorrhiza, salvia miltiorrhiza+poria cocos, atractylodes+poria cocos, alisma+poria cocos, such as three ingredients and four herbs to dogwood, alisma and poria cocos+radix rehmanniae radix rehmanniae, paeonia suffruticosa+dogwood, poria cocos, cortex moutan+dogwood, alisma+poria cocos, cortex moutan, rhizoma alismatis+poria cocos+radix rehmanniae, fructus schisandrae, radix pseudostellariae+radix ophiopogonis, radix rehmanniae, etc.Conclusion:(1) the effect of Type2Diabetes Mellitus With Dyslipidemia risk factors include: blood sugar,age, BMI, blood fat rise, diabetes duration, smoking history, drinking history, high blood pressure.(2) Type2Diabetes Mellitus With Dyslipidemia to the symptoms of dry mouth, fatigue, more drink, urinate frequency, constipation, poor sleep, blurred vision, dizziness, headache, numbness, limbs cold, limb edema, night to urinate. Tongue with dark red tongue, red tongue, light and dark tongue. Moss as to thin white moss, thin yellow moss, white greasy moss is given priority to. Pulse condition with heavy fine veins, string thin vein, string is rare.(3) Type2Diabetes Mellitus With Dyslipidemia parting with Ⅱ a and Ⅱ b, Ⅳ type. (4) Type2Diabetes Mellitus With Dyslipidemia of TCM syndrome types are mainly qi and Yin deficiency and blood stasis syndrome, qi deficiency blood stasis evolved into the Yang deficiency, blood stasis, visible guiding the diabetic lipid metabolic disorder of blood stasis.(5) Type2Diabetes Mellitus With Dyslipidemia of therapeutic principle with qi and nourishing Yin, promoting blood circulation to remove blood stasis, eliminating phlegm expelling dampness, WenYangLi water mainly.(6)Type2Diabetes Mellitus With Dyslipidemia disease treatment every period with qi and nourishing Yin,promoting blood circulation to remove blood stasis and water permeabilitywetdrugs:shengdi, fuling, danshen, huangqi, maidong, danggui, baishu, chichao, chuanxiong, taizishenetc. Combinationwithradixscrophulariae, xuanshen, maidong, danggui, shengdi, danshen, shanzhuyu, fuling, zexie, mudanpi, wuweizi, taizishen mainly.(7) Type2diabetes mellitus and lipid metabolic disorder disease every period of each card on behalf of the prescriptions for promoting blood circulation to remove blood stasis, qi and nourishing Yin, heat phlegm, WenYangLi water effective prescriptions:danshenyin, yunvjian, shengmaiyin, liuweidihuangtang, erchentang, siwutang, wulingsan away.