The Preliminary Investigation Of The Effectives And Possibilities Of High Temperature Superconducting Quantum Interference Device In The Diagnosis Of Unstable Angina Pectoris

Coronary heart disease (CHD) is a kind of the most commoncardiovascular disease that has serious damage to health. At present,coronary angiography (CAG) is the most accurate method for the diagnosisof CHD, but the trauma is bigger. The sensitivity and accuracy oftraditional inspection methods, such as ordinary electrocardiogram (ECG),ultrasonic cardiogram (UCG) are low. Based on biot-savart law, electricalactivity creates a weak magnetic field around it. Magneto cardiogram(MCG) is a kind of new technology that detect weak magnetic fieldproduced by cardiac electrical activity. Periodic mechanical activity of theheart can produce a weak biological electric current. MCG can determinethe weak magnetic field produced by the heart activity. In1963Baule andMefee first recorded the faint MCG on the human body chest wall. Afterfurther research of several generations, MCG technology has becomegradually mature, Germany, Japan, the United States, China and othercountries are applying it in the clinical diagnosis of it. In recent years,MCG in myocardialischemia research of CHD have improved. Amongthem, the research on the early diagnosis of unstable angina pectoris (UAP)is so striking that it become a new hot spot in the study of coronary heartdisease (CHD) in the world at present. Especially the successfuldevelopment of the high temperature superconducting magnetocardiogram(HT-MCG), further reduces the cost of testing and expand the clinicalapplication.This experiment is used to explore the effect and feasibility on the clinical application of HT-MCG in the diagnosis of unstable anginapectoris(UAP), and compare with ECG and UCG. Choose60patients whohave been diagnosed of UAP after coronary arteriography examination, andwho don’t have diseases like non ST-elevation acute myocardial infarctionheart failure, hypertension, cardiomyopathy and various kinds ofarrhythmia patients.58non-CHDs who have no stenosis of coronary arterybranches. The diagnostic criteria for UAP at least one coronary artery’smain branch has stenosis above70%.Keep a record of the118people’sages, gender, height, weight, blood glucose, blood lipids, smoking history,and medical history. They need to take the HT-MCG examination, normalresting ECG and UCG examinations. Analyze quantitatively two indexes ofthe MCG: the ACTM and the RAM, and put the test result into statisticalanalysis. We draw a few results:(1)Groups of clinically relevantinformation including ages, gender, height, weight, blood glucose, bloodlipids, smoking history, and medical history don’t have differ much （P>0.05）.(2)The average classification of the group with UAP is(3.12±0.84), while the contrast group is （1.56±0.72）, the differencebetween the two groups has statistical significance（P＜0.05）The ratio ofabnormal MCG is (69.43±25.58)%,while the contrast group is(37.14±20.75)%, the difference between the two groups also has statisticalsignificance（P＜0.05）.(3) Of the60patients with UAP,49have abnormalMCG （81.7%）,the ECG of40patients show ischemiamyocardial(abnormal Q-wave and change in ST-T)(66.7%),the UCG of27patients show segmental wall motion abnormalities（45.0%）,the positiverate of the diagnosis of UAP with HT-MCG is much higher than ECG andUCG（P＜0.05）.This study suggests that:1. ACTM and RAM can be used as importantindicators in the diagnosis of UAP with HT-MCG.2. HT-MCG is morehelpful than ECG and UCG in the diagnosis of UAP.3. HT-MCG willoffer a noninvasive way of diagnosing UAP.