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Research On The Relationship Between Coronary Slow Flow And Vascular Inflammatory Cytokines

Posted on:2015-07-27Degree:MasterType:Thesis
Country:ChinaCandidate:M XuFull Text:PDF
GTID:2284330467467157Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective: By detecting, comparing coronary slow flow group and the group ofpatients with normal blood vascular inflammatory cytokines hypersensitivity C--reactiveprotein (hs-CRP), interleukin-1(IL-1),interleukin-6(IL-6) levels,to investigate thecorrelation and clinical significance of coronary slow flow (CSFP) and vascularinflammatory factors. Methods: Selected229cases of coronary angiography in patientswith no significant stenosis in hospital,Measured using coronary angiography TIMI flowand corrected TIMI frame count,Patients were divided into epicardial coronary diseasebut there are no obvious group of102cases of coronary blood flow is slow,Epicardialcoronary blood flow is completely normal and the normal group127cases,Collect clinicaldata,to detect levels of vascular inflammatory factors hypersensitivity C-reactive protein,interleukin-1, interleukin-6.Results: Detection level of Hypersensitivity C-reactiveprotein, interleukin-1, interleukin-6in Coronary slow flow group,the results showed thatthree kinds of vascular inflammatory factors were higher than normal blood flow,Correlation analysis showed that coronary blood flow velocity and vascular inflammatorycytokine levels were negatively correlated, Differences between the two groups of patientswith vascular inflammatory factors were statistically significant(P<0.05)。Conclusion:Coronary flow velocity is closely related to the level of vascular inflammatory factors,Vascular inflammatory cytokine levels in patients with slow blood flow was higher thanthe normal group.
Keywords/Search Tags:Coronary artery, Slow blood flow, Vascular inflammatory cytokines
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