Studies About Retinol Binding Protein4between Type2Diabetes Mellitus And Cerebral Infarction

Objective：To explore the type2diabetes mellitus and cerebral infarction patients serum retinol bindingprotein4(RBP4) levels and its significance.Methods：Select in November2012-July2013in the first affiliated hospital of shihezi university of30patients with type2diabetes mellitus (DM),30patients with cerebral infarction (CI group) and30patientswith type2diabetes mellitus and cerebral infarction group (DM+CI) medical healthy people (controlgroup) and30cases of the same period. Record each client’s general information and laboratory test results,comparison between groups of serum RBP4levels; Using Spearman ’s correlation analysis of RBP4relatedfactors; The binary classification Logistic regression analysis the influence factors of type2diabetescomplicated with cerebral infarction.Results：(1) the client three out of four acyl glycerin (TG), low density lipoprotein (LDL), RBP4,glycosylated hemoglobin (HbA1c), urinary inhibition C, between homocysteine (Hcy) levels havedifference (P <0.05); The RBP4levels in patients with DM+CI group were higher than other three groups(P <0.05).(2) falls below group blood sugar control (HbA1c>6.5%) RBP4level higher than standardblood sugar control groups (mg/L (106.0-23.1) and (87.8+/-32.5mg/L, t=3.539; P=0.001).(3) serumTC, TG, LDL levels are positively correlated with RBP4(r value was0.430,0.432and0.430, respectively;P=0.001).(4) in patients with DM DI whether as the dependent variable of the binary classificationLogistic regression analysis found that RBP4(OR=1.023, P=1.023) and Hcy (OR=1.130, P=1.130) arethe biological indexe of diabetic cerebral infarction.Conclusion：(1) in patients with type2diabetes mellitus and cerebral infarction serum RBP4levels, promptRBP4can be used as a predictor of type2diabetes complicated with cerebral infarction.(2) serum RBP4levels associated with blood glucose control is not up to standard, tip need to change the hypoglycemic plan;(3) serum TC, TG, LDL levels and RBP4levels were positively correlated, suggests the importance ofblood lipid therapy.