Systematic Evaluation Of Clinical Basis For The Treatment Of Coronary Heart Disease Syndrome Of Exuberance Of Heart Fire Qing Xin Fire Method

Objective: coronary heart disease (CSP) traces the origin and development ofexcessive heart fire theory，construction of CHD (chest pain) knowledge system excessiveheart fire "pathogenesis-syndrome-drug"， on the basis of which， the furtherdevelopment of Qingxin fire method in the treatment of coronary heart disease (CSP)evaluation system of the efficacy and safety of fire flaming syndrome thus， Qingxin fireDecoction in treating coronary heart disease (CSP) provide the basis.Methods:1using the method of literature knowledge discovery， syndrome ofexuberance of heart fire elaboration in ancient medical books， according to the study ofthe origin and development of ancient three period，90years ago， after90years，combing the excessive heart fireand find the correlation between syndrome pathogenesis，syndrome and treatment， construction of CHD (chest pain the knowledge system ofexcessive heart fire ") theory of pathogenesis-syndrome-drug".2by means of electronicand manual search methods， a comprehensive search method in treating coronary heartdisease with Qingxin fire published in domestic journals in recent20years (CSP) is asystematic review of randomized controlled trials excessive heart fire permit， inaccordance with the method recommended by the manual evaluation of Cochrane systeminto the risk of bias research， Meta-analysis was carried out on the overall effect severalresearch results using RevMan5.2.6software analysis， funnel plot.3collection of testcase， reflect the Qingxin fire method in treatment of coronary heart disease (CSP)application value on the clinical syndrome of exuberance of heart fire. Results:1of CHD (chest pain) excessive heart fire theory is a long history ofevolution， has constructed "the pathogenesis-syndrome-drug" system， and provideclinical support theory basis for the application of Qingxin fire method in clinical treatmentof coronary heart disease， provide useful references for the clinical diagnosis andtreatment.2systematic review included15randomized controlled clinical trial， a total of1680patients， buttheir methodological quality is low.Analysis of curative effectevaluation of angina improvement combined effect of the amount of RR Meta-(Random)and95%CI:1.20[1.13，1.27] RD=0.16; ECG efficacy evaluation of combined effect ofthe amount of RR (Random) and95%CI RR=1.32[1.2，1.44] RD=0.20; TCM symptomsimproved efficacy evaluation of combined effects of RR (Random) and95%CI:RR=1.34[1.06，1.69] RD=0.23.Only2cases of adverse reactions in the15study， themajor adverse reactions were diarrhea， but the stool normal. The adverse reaction withoutspecial treatment， or after discontinuation of subside， the rest of the reported no adversereactions. Through examples of test case， demonstrate clinical dialectical therapy can getgood therapeutic effect.Conclusion: This paper clarifies the origin and development of CHD (chest pain)excessive heart fire theory， established the theory of "disease-syndrome-drug"knowledge system， a systematic evaluation of Qingxin fire method in the treatment ofcoronary heart disease (CSP) the clinical efficacy and safety of the syndrome ofexuberance of heart fire， thus Qingxin fire prescription treatment coronary heart disease(CSP) provide the basis.