Research On Famous TCM Gynecologies’ Diagnosis And Treatment Of Polycystic Ovary Syndrome

Polycystic Ovarian Syndrome is the characteristic lesion which has a Kaohsiung hormones,ovulatory dysfunction and polycystic ovary.Clinical manifestations are varieties,such as menstrual disorde, infertility, hirsutism, obesity, etc.The disease involves multiple systems, and it is complex for clinical diagnosis and treatment. In the ancient literature of TCM disease had not described in Polycystic Ovary Syndrome,that mainly according to clinical manifestations.It can be attributed to be on the treatment of hypomenorrhea, amenorrhea, infertility, menstrual period, etc.In recent years, the disease of Chinese medicine treatments is gradually highlight its advantages, which can fundamentally relieve the patient pain.Therefore,the expriences of the treatment of this disease of gynecological medicines should be arranged systematically, which include in etiologies and pathogenesis, treament, medicine, to provide a reference for the future of Chinese medicine in the treatment of disease.OBJECTIVESWe chose 30 famous TCM experts academic experience inheritance from the first to the fifth batch of old to guide the work of the teacher in the selection, which are mainly engaged in the gynecology of TCM.It can grasp the overall experiences of diagnosis and treatments of Polycystic Ovary Syndrome.It is a good way to summarize their understandings of etiologies and pathogenesis of the disease, treatment, medical diagnosis of this disease and analysis of the syndromes of TCM, and take thier prescription frequency statistics and the rules of drug analysis in order.It provides a reference for the related basic theory and clinical medicine.METHODS1 Literature ReviewWe can get related literature from the use of cyber source library and library.Then, we could summarize the main etiologies and pathogenesis and therapeutic principles by collecting and finishing 30 masters in diagnosis and treatment of Polycystic Ovary Syndrome.2 Data Mining Research of arthralgia prescriptionIt conforms to the standard of the collected data using the software of its own statistical analysis, followed by the use of "TCM inheritance auxiliary platform (V2.5)"software.The overall data analysis including the analysis of frequency statistics and rules.All the cases are divided into three groups of hierarchical data analysis including late menstruation, amenorrhea, uterine bleeding.In order to explore the drug experience gynecologic famous experts in the diagnosis and treatment of Polycystic Ovary Syndrome.RESULTS1 the Result of Literature Review①Polycystic Ovary Syndrome of TCM etiologies have four points.They are congenital factors, lifestyle factors, emotional factors, physical factors.The lifestyle of factors including improper diet, work and rest, drug or operation injury.②Polycystic Ovary Syndrome occurred more than three dirties treatments from kidney, liver, spleen.And the most important pathogenesis is kidney.Disease locations are also involved in the Chongren, the uterus, and the main risk factors are phlegm and blood stasis.③Treatment of this disease can be summarized as the following three aspects.Each person has own treatment.The combination of disease and syndrome and the body use together.Combine prevention with control and keep the mood happy.2 Results Prescription Data Mining①There are 138 cases in this study.It includes 387 prescriptions,229 kinds of traditional Chinese medicine and using drug 5596 times.Among them, the frequency of use of traditional Chinese medicine in 100 a total of more than 16, respectively: Danggui, Tusizi, Xiangfu, Chuanxiong, Baishao, Shudihuang, Fuling, Gouqizi, Dansheng, Yinyanghuo, Niuxi, Baizhu, Gancao, Bajitian, Shanzhuyu, Yimucao.②20～30 years old patients are the main ages for Polycystic Ovary Syndrome seeing doctors, accounting for 69.57% of the total.The puberty and reproductive age women are the main crowd to go to the hospital.③There are 14 used a combination of drugs which can treat the patients of Polycystic Ovary Syndrome.They are Danggui, Xiangfu, Tusizi, Chuanxiong, Shudi, Gouqizi, Baishao, Dansheng, Yingyanghuo, Niuxi, Shanzhuyu, Baizhu, Bajitian.Bushenhuoxue drugs are often used much in the overall top 30 drugs.Invigorating spleen and regulating qi and removing dampness could be compatibility of medicines.Sometimes,doctors like to use medication with local drugand and experience of drug.④There are 31 Syndromes of traditional Chinese Medicine in 138 cases, and the frequencies are total 227 times.We can find something in the distribution of TCM Syndromes.This disease occurs in viscera function disorder, the operation of Qi blood and body fluid out of order, Chong and Ren injury, Cell pulse damage.In 227 Syndrome of traditional Chinese Medicine, phlegm dampness syndrome appears 82 times (36.12%), blood stasis syndrome appears 52 times(22.91%).In 138 cases, deficiency syndrome appears 18 times (13.04%).Empirical syndrome appears 17 times (12.32%).Intermingled deficiency and excess syndrome appears 103times (74.64%)TCM syndrome factor analysis:there are 6 syndrome elements of disease location in the included literature, and the frequencies are total 222 times.Disease in kidney are significantly more than other organs in the first place, the second is liver, the third is spleen.The disease locations in Chongren, uterus, heart appear 32 times.Two viscera comorbidities appear 50 times.Liver with kidney and spleen with kidney are in the forefront.They appear 47 times in total.There are 8 syndrome elements of disease nature, and the frequencies are total 212 times.Phlegm is in the first, blood stasis ranked second.They appear 134 times.⑤Menstrual disorders in three groups of TCM syndrome elements extraction results:menstruation groups emphasis on kidney deficiency and blood stasis syndrome.The amenorrhea groups emphasis on spleen dampness.Uterine bleeding groups emphasis on kidney deficiency and blood stasis syndrome.⑥Results of menstrual disorder treatment in the three groups:menstruation group use frequency in the top 10 are Danggui, Tusizi, Xiangfu, Fuling, Chuanxiong, Baishao, Gouqizi, Shudihuang, Danshen, Niuxi.The amenorrhea group medication frequency in the top 10 are Danggui, Xiangfu, Tusizi, Fuling, Chuanxiong, Danshen, Niuxi, Shudi, Gancao, Baishao.The frequency of bleeding group in the top 10 are Gancao, Shanzhuyu, Baishao, Gouqizi, Danggui, Tusizi, Dangshen, Xiangfu, Chuanxiong, Shudihuang.The same drugs in the three groups are Danggui, Xiangfu, Tusizi, Chuanxiong, Shudihuang. Cangfu Daotan pill often can be used in spleen deficiency phlegm amenorrheathe.⑦Result of the composition rules menstruation disorders of three groups of Association Rule Algorithm based on the analysis.The same drug combinations in three groups of this analysis are Chuanxiong->Danggui, Shudi->Danggui, Shudi、 Tusizi->Danggui.We can use these drug combinations universally.⑧When we support three groups respectively, dynamic display each prescription rules.Amenorrhea group focused on increasing spleen dampness, activating blood flow strength.Menstruation group strengthen force of warming kidney and invigorating spleen and regulating qi.Uterine bleeding group that nourishing the liver and kidney at the same time, focus on replenishing qi to invigorate the spleen, and to secure hemostasis.CONCLUSION1 Polycystic Ovary Syndrome of TCM etiologies have four points.They are congenital factors, lifestyle factors, emotional factors, physical factors.The lifestyle of factors including improper diet, work and rest, drug or operation injury.2 Polycystic Ovary Syndrome occurred more than three dirties treatments from kidney, liver, spleen. And the most important pathogenesis is kidney.Disease locations are also involved in the Chongren, the uterus, and the main risk factors are phlegm and blood stasis.3 Treatment of this disease can be summarized as the following three aspects.Each person has own treatment.The combination of disease and syndrome and the body use together.Combine prevention with control and keep the mood happy.4 Menstrual disorders in three groups of TCM syndrome elements extraction results:menstruation groups emphasis on kidney deficiency and blood stasis syndrome.The amenorrhea groups emphasis on spleen dampness.Uterine bleeding groups emphasis on kidney deficiency and blood stasis syndrome.The same drugs in the three groups are Danggui, Xiangfu, Tusizi, Chuanxiong, Shudihuang.Cangfu Daotan pill often can be used in spleen deficiency phlegm amenorrheathe.5 There are 14 Used a combination of drugs which can treat the patients of Polycystic Ovary Syndrome.They are Danggui, Xiangfu, Tusizi, Chuanxiong, Shudi, Gouqizi, Baishao, Dansheng, Yingyanghuo, Niuxi, Shanzhuyu, Baizhu, Bajitian.Bushenhuoxue drugs are often used much in the overall top 30 drugs.We can use drug combinations of Chuanxiong、Danggui, Shudi、Danggui, Shudi、Tusizi、 Danggui universally.