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Curative Effect Of Bu Xin An Shen Prescriptions On Treatment Of Angina Pectoris After PCI Of Deficiency Of Both Qi And Yin

Posted on:2016-03-31Degree:MasterType:Thesis
Country:ChinaCandidate:J B XiaFull Text:PDF
GTID:2284330464955941Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:PDF Full Text Request
BackgroundCoronary artery disease (CHD for short) is a common disease in clinical practice, and it’s also one of the important causes of death. World Health Organisation statistics show that about 17 million people die each year from cardiovascular disease. The disease occurs mainly in the age after 40, and more men than women in recent years have been significant upward trend and a younger age trend. Percutaneous coronary intervention (PCI) has become one of the main methods of treatment of coronary heart disease in recent years, with the gradual perfection of the various Interventional devices and technology, and interventional therapy of coronary heart disease especially in the past 20 years has seen rapid development in our country. PCI postoperative chest pain is a common phenomenon in clinical, long-term follow-up with an incidence of up to 50%. Despite once again found stents coronary angiogram coronary "no abnormality",but persisted with angina pectoris, and medications are also often fail to effect. Traditional Chinese medicine in treatment of angina pectoris after PCI has a unique advantage,to materialize the advantanges of traditional Chinese medicine in treatment of angina pectoris after PCI therapy, so the issue of Bu Xin An Shen prescription treatment of type of deficiency of both Qi and Yin after PCI observation on the curative effect of angina pectoris.ObjectiveThis study aims to systematize the domestic and international clinical research after PCI, and summary treatment of angina pectoris after PCI in recent years on the basis of clinical experience, research, information and documentation, than,to form a type of deficiency of both Qi and Yin treated by TCM clinical treatment after PCI, angina pectoris, explore Anshen therapy type of deficiency of both Qi and yin of angina pectoris treated with Chinese medicine after PCI rules.Research contents and methodsRandomized control study, collected according to the inclusion criteria from: wangjing hospital emergency of China Academy of traditional Chinese medicine in 63 cases, divided into two groups by random number table (31 cases) and control groups (32 cases). Control group used control group gives select Crown pulse intervention treatment success patients, operation hou General to worship aspirin (100mg/tablets) oral daily once each a, sulfuric acid hydrogen chlorine h gray (75mg/tablets) oral daily once each a, Atto cutting he Ting calcium (20mg/tablets) oral each late a, single nitric acid ISO sorbic vinegar sustained release tablets (20mg/tablets) oral daily two times each 20mg, beauty of intravenous metoprolol sustained release tablets (25mg/tablets) oral daily two times each half tablets, Fosinopril tablets (5mg/tablets) taken orally once daily. Testing group in the medical treatment group and on the basis of Bu Xin An Shen prescription, One dose per day, sooner or later you 2 times and then drunk, selection of China Academy of traditional Chinese medicine decocting-free homemade decoction and granules; for an observation period to 28 days. Recorded outcome measures and data analysis, comprehensive analysis of its efficacy and safety.Result:1 Comparison of the baseline of the two groupsPatients age, sex, duration of illness, past history, allergies, respiration, pulse, blood pressure, Seattle angina questionnaire, ECG, type of deficiency of both Qi and Yin syndrome score rating distribution showed no statistically significant difference between the groups (p>0.05), has comparable.2 The two groups after treatment efficacy compared2.1 The two groups before and after treatment in the Seattle angina scale score ComparisonThe Seattle angina questionnaire test group and control group scores,and showed: understanding degree of test group in activities to limit the extent, angina stability, an-gina pectoris, treatment satisfaction, disease score are better than the control group, an-d the two groups was statistically significant difference (P<0.05) improvement.2.2 Comparison of TCM Qi Yin deficiency symptom score of two groups before and aftertreatmentAfter the treatment of TCM Qi Yin deficiency symptoms,the patients in test grou p with heart palpitations,chest tightness,shortness of breath,dizziness,insomnia score b-etter than the control group,the difference was statistically significant (P< 0.05).The t wo groups after treatment in the tongue,pulse score improvement was no significant d ifference (P>0.05).In the traditional Chinese medicine symptoms overall curative ef-fect, the test group and control group, P<O.05,with statistical significance,showed t-h at the overall efficacy of TCM symptoms in the experimental group than the control g roup.2.3 The overall curative effect of TCM symptomsAfter 4 weeks of treatment, in the experimental group of 31 cases,11 cases were markedly effective,19 cases effective,1 cases ineffective, aggravated in 0 cases, the total efficiency of 96.77%; in control group of 32 cases,5 cases cured,21 cases effective,5 cases ineffective, aggravated in 1 cases, the total efficiency of 81.25%, the difference was statistically significant (P<0.05).It indicates that the overall effect of the experimental group was better than the control group.2.4 Comparison of ECG efficacy before and after treatment in two groupsAfter 4 weeks of treatment, in the experimental group of 31 cases,7 cases were markedly effective,20 cases effective,4 cases ineffective, aggravated in 0 cases, the t-otal efficiency of 87.10%; In control group of 32 cases,5 cases cured,18 cases effecti-ve,8 cases ineffective, aggravated in 1 cases, the total efficiency of 71.88%, the diffe r-rence was statistically significant (P<0.05).It indicates the ECG efficacy experiment-al group was better than the control group.Conclusions1. BU Xin An Shen combined Western medicine in the treatment of PCI postoperative qi and Yin deficiency type angina pectoris limit state stable angina pectoris degree to improve the activity Angina pectoris attack Treatment satisfaction degree of disease cognition degree have obvious effect.2. BU Xin An Shen combined Western medicine in the treatment of PCI postoperative qi and Yin deficiency type angina pectoris with good security.3. BU Xin An Shen combined with Western medicine in treating angina of Qi-Yin deficiency type after PCI operation safe and efficient, can develop into in-hospital preparations so that its clinical application and promotion.
Keywords/Search Tags:angina pectoris, Qi and Yin deficiericy syndrome, BU Xin An Shen prescription, traditional Chinese medical treatment
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