Clinical Research Of Infusing Fresh Or Old Red Cell Suspension Effect On Patients’ Postoperative Prognosis And Outcome

Objective:Evaluation of infusion of fresh or old red cell suspension and different volume of blood transfusion on the prognosis of patients with surgical. Methods:Selected 273 patients underwent the first elective orthopedic surgery from the first affiliated hospital of Xinjiang medical university from January 2013 to December. Accepting criteria,15years-65years,no limitation for race and gender, ASA I-III grade, need transfusion of red blood cell ≤10U. According to the oldest storage age of any RBCs transfused:patients who received only RBCs stored for ≤14 days were grouped to the Fresh, those who received only RBCs stored for>14 days were grouped to the Old. According to the volume of blood transfusion were divided into ≤2 U,3-4 U,≥5 U three groups. Record the demographic and clinical features of the patients, and to compare two groups length hospital stay, the rate of ICU shift, pulmonary infection occurred, postoperative transfusion rate, incision healing condition and major adverse cardiovascular events. Results:There was statistical differences in postoperative 24h hemoglobin, postoperative transfusion rate, pulmonary infection occurred and major adverse cardiovascular events between the Fresh and Old group (P<0.05). A trend of increasing complication rate was observed with more units transfused, especially≥5UConclusion:Infusion of old red cell suspension has a certain impact to the surgery patients’ postoperative complications. The volume of blood transfusion is consistently associated with adverse outcome.