The Association Between The Uygur Patients With Schizophrenia And CMYA5

Objective:To investigate the association between Cardiomyopathy associated 5 (CMYA5) and schizophrenia in the Uygur Chinese population. Methods:rs3828611, located in the CMYA5 gene, was detected by Taqman assays in 684 schizophrenia patients and 678 healthy controls from Uygur Chinese population.The positive and negative symptoms scale (PANSS) was used to evaluate patients’ symptoms. Results:Neither the genotype nor allele frequencies of rs3828611was significant different between the patients and the controls (P>0.05). The differences were not significant in each gender subgroup or in each age (teenager and adult) subgroup (P>0.05). The total score and the sub scores of PANSS were not significantly different among patients with different genotype groups (P>0.05).Conclusion:There is no association between CMYA5 and schizophrenia in the Uygur Chinese population.