Safety And Feasibly Of Single Incision Laparoscopic Surgery Versus Conventional Multiport Splenectomy-A Meta-analysis And Systematic Review

Objective:systematically evaluate safety and feasibly of single-incision laparoscopic surgery (SILS) versus conventional multi-incision(LS) splenectomy. Methods: Databases including PubMed、EMbase、Medline、SCI、CNKI、WanFang Data, and The Cochrane Library were searched to collect the randomized controlled trails (RCTs) and randomized controlled trails (non-RCTs) about SILS versus conventional multiport splenectomy. The retrieval time was from inception to october 2014. The studies were screened according to the inclusion and exclusion criteria, Then the meta-analysis was conducted using RevMan 5.2.5 software. Results:A total of 7 non-RCTs involving 202 patients were included. The results of meta-analysis showed that There were no significant differences in operative time, MD=-9.69;95%CI=-74.88,55.51; P=0.77, amount of intraoperative bleeding, MD=-27.82; 95%CI=-101.23,45.59; P=0.46, length of hospital stay, MD=-0.47; 95%CI=-2.12 to 1.18; P=0.58, The cost of treatment, MD=-0.14; 95%CI=-0.42,0.14; P=0.33, Size of spleen, MD=60.07; 95%CI=-0.42,0.14; P=0.33, But The degre of postoperative pain, MD=-1.41; 95%CI=-99.76,219.91; P=0.46) and postoperative pass gas time, MD=-0.47; 95%CI=-0.84,0.10; P=0.01 have significant differences in two group.Conclusions:SILS is safe and feasible. However, for the quantity and quality limitation of the included studies, this conclusion still requires to be further proved by performing large scale and high quality RCTs.