A Case Report Of Primary Gastric Malignant Lymphoma And Literature Review

Objective:To investigate the clinical characteristics of Primary Gastric Malignant Lymphoma, imaging inspection, classification, pathogenesis, diagnostic essential and therapy programs etc. For the sake of raise the level of diagnosis and therapy of Primary Gastric Malignant Lymphoma.Methods:The clinical data of one patient suffered from Primary Gastric Malignant Lymphoma were retrospectively analyzed, and combined with related literature retrospect and summary.Data:An elderly women patient, who had intermittent abdominal pain and discomfort for more than one months. Prior to admission, in the other hospital gastroscopy examination revealed gastric ulcer. Our hospital outpatient examinations esophagogastroduodenoscopy showed gastric ulcer lesions (Ca?). Pathological biopsy showed:conform to the gastric ulcer.Interventions:To carry; out the routine examination and chest X-ray, electrocardiogram, gynecological ultrasound, lymphonodus ultrasound, CT Scan-Abdomen, repeatedly electronic gastroscopy and pathological biopsy inspection, for purpose of acquirement of explicit diagnosis. Meanwhile, supportive therapy included acid suppression, Helicobacter pylori extirpation, nutritional support, and symptomatic therapy was used. After many times of gastroscopy and pathological biopsy inspection, the diagnosis was certificated, into the Department of Hematology to give chemotherapy scheme of FCR(R 500mg d0 + Fluda 30mg dl-3 + CTX 300mg dl-3), saving closely observe and follow.Results:Esophagogastroduodenoscopy showed:gastric lymphoma. Pathological examination of living tissue revealed:gastric lymphoma of diffuse large B cell, sources of the germinal center, highly malignant. Abdominal CT illustrated:1.the lining of stomach local thickening saving mild reinforcement, conform to lymphoma of stomach; 2.the liver stomach clearance, retroperitoneal and mesenteric area, beside the bilateral iliac blood vessels and multiple lymph node enlargement; 3.pelvic effusion; the left kidney cyst. Finally, the patient was diagnosed as non-Hodgkin’s lymphoma (primary gastric) diffuse large B cell lymphoma Ⅱ group B.Conclusion:The clinical characteristics of Primary Gastric Malignant Lymphoma lacks specificity. Primary Gastric Malignant Lymphoma can be confirmed with utilization pathological biopsy. But, due to lesions of gastric malignant lymphoma located in the submucosal lymphoid tissue, leading to take biopsy there exist certain difficulties. Thus, the existing challenges of diagnosis are quite obvious, accompanied a higher misdiagnosis rate. For the sake of boost the precision of diagnosis, it is indispensable to take biopsy many times, multi-point, deep tissue when esophagogastroduodenoscopy is employed in the consideration of malignant lesions.