Multivariate Analysis On Recurrent Hemorrhage After Operation Of Hypertensive Intracerebral Hemorrhage

Objective: To analyze the influence of related factors on recurrent hemorrhage after operation of hypertensive intracerebral hemorrhage, and investigate the countermeasures against recurrent hemorrhage.Methods: The patients comes from the First Affiliated Hospital of Anhui Medical University, from 2010 to 2014. Recurrent hemorrhage after operation of hypertensive intracerebral hemorrhage is 20 cases, none is 104 cases. Male 72 cases, female 52 cases,age 32-76 years old, average(57.2±10.3)years old. Hemorrhage site, lobe 33 cases,basal ganglia 37 cases, thalamus 54 cases. Timing of operation, within 6 hour is 25 cases, in 6-12 hour 81 cases, in 12-18 hour 10 cases, in 18-24 hour 8 cases. Operation method, Large craniotomy 82 cases, small bone window 42 cases. Hemostasia difficulty is 27 cases, satisfactory 97 cases. Blood pressure control better 48 cases, good 47 cases,dissatisfied 29 cases. 124 patients with surgical treated hypertensive intracerebral hemorrhage were analyzed retrospectively. Logistic regression analysis was applied to analyze the function of various possible factors that might induce recurrent hemorrhage.Result: The incidence of recurrent postoperative hemorrhage was16.1%.Univariant logistic analysis disclosed that the period between initial bleeding to operation, the hemorrhage site and coagulation factor disorders, difficulties met during the operation and inadequate hemostasis, and postoperative blood pressure fluctuation significantly related with recurrence of hemorrhage(P<0.05).Multivariate logistic regression analysis showed that timing of operation, difficulties met during theoperation and inadequate hemostasis and postoperative blood pressure fluctuation were risk factors of recurrent hemorrhage(P<0.05).Conclusion: Timing of operation, difficulties met during the operation and inadequate hemostasis and postoperative blood pressure fluctuation were risk factors of recurrent hemorrhage. The optimal operative time, strict hemostasis in operation and appropriate postoperative blood pressure control are important measures in preventing recurrent hemorrhage.