| Objective: To explore the feasibility and diagnostic value of the fragmented QRS complexes(f QRS) in the diagnosis of coronary heart disease,and the differences in the incidence of f QRS between Han and Zhuang patients with coronary heart disease.Methods: A retrospective analysis of two hundred and twenty-eight patients who underwent isolated coronary angiography in the first Comprehensive Ward of Guangxi Zhuang Autonomous Region People’s Hospital from January 2013 to June 2014. The patients were divided into the Coronary heart disease(CHD) group and non-CHD group. The CHD group was composed of one hundred and fifty-seven patients, including one hundred and five Han patients and fifty-two Zhuang patients. The non-CHD group was composed of seventy-one patients, including forty-three Han patients and twenty-eight Zhuang patients. The aim of the present study was to detect the differeces in the incidence of f QRS between CHD and non-CHD, and the relationship between f QRS and coronary heart disease, coronary artery lesions(location, extent, count), nation(Han, Zhuang) and clinical related factors.Results: The average age in CHD group is older than that in non-CADgroup(63.8±9.8 vs. 57.5±10.3; P<0.05). The proportion of male patients in CHD group is higher than that in non-CHD group(72.0% vs. 50.7%; P<0.05).The proportion of the subjects with diabetes in CHD is higher than the non-CHD with diabetes(31.2% vs. 8.45%; P<0.05). There is no difference in the proportion of nation(Han, Zhuang), hypertension and high cholesterol between CHD and non-CHD(P>0.05). The incidence of f QRS in CHD group is significantly higher than that in non-CHD group(72.0% vs. 35.2%; P<0.01). In the diagnosis of the CHD, the sensitivity is 72.0%, the specificity is 64.8%, the positive predictive value is 81.9% and the negative predictive value is 51.1%.The incidence of f QRS in Han is 60.8%, Zhuang is 60.0% in the total patients,the incidence of f QRS in Han is 72.4%, Zhuang is 71.2% for the One hundred fifty-seven CHD patients, the incidence of f QRS in Han is 32.6%, Zhuang is39.3% in non-CHD. There is no significant different between Han and Zhuang(P>0.05). There are significant differences in the incidence of f QRS between anterior, inferior and anterior+inferior in CHD and non-CHD(P<0.01),but there are no differences between lateral, anterior+lateral, lateral+inferior,anterior+lateral+inferior(P>0.05). The incidence of f QRS in inferior is higher than that in anterior and lateral in both CHD and non-CHD groups(P<0.05).There is no differences in incidence of f QRS between left anterior descending(LAD), left circumflex artery(LXC) and right coronary artery(RCA)(P>0.05),but the incidence of f QRS in LAD is higher than LCX and RCA with CHD(P<0.05). There is no differences in the incidence of f QRS among single, two or three coronary artery(P>0.05). The incidence of f QRS is not related with age,sex, hypertension, diabetes and high cholesterol(P>0.05).Conclusion: The f QRS is an ECG indicator which can be used as a predictor of CHD, but it can not predict the extent of disease and the number ofdiseased vessels. The f QRS has a consistent diagnostic value for CHD in Han and Zhuang. The incidence of f QRS in CHD is higher than non-CHD among anterior, inferior and anterior+inferior. The incidence of f QRS in inferior is higher than that in anterior and lateral in both CHD and non-CHD groups. The incidence of f QRS in LAD is higher than LCX and RCA with CHD. The incidence of f QRS is not related with age, sex, hypertension, diabetes and high cholesterol. |
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