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Clinical Analysis Of 184 Patients Of Malignant Tumor With Venous Thrombotic Embolism

Posted on:2016-08-17Degree:MasterType:Thesis
Country:ChinaCandidate:C Z ShaoFull Text:PDF
GTID:2284330461965269Subject:Oncology
Abstract/Summary:
Objective:To explore the guangxi tumor hospital between January 2010 and January 2013 malignant tumor with 3 years of venous thromboembolism (VTE) of disease clinical characteristics, diagnosis, treatment, prognosis and prevention of lung cancer and gynecological tumor, the digestive tract tumor, breast cancer and other tumors combined the incidence and prognosis of patients with VTE, improve tumor merger VTE awareness and improve the prognosis of patients with tumor.Methods:Were retrospectively analyzed in guangxi medical university affiliated tumor hospital between January 2010 and January 2013 were of the clinical data of 184 patients of malignant tumor with VTE, analyze the clinical characteristics, treatment and prognosis, and so on and so forth.Result:Our three years, a total of 24595 patients with malignant tumor treated with combination of VTE patients 184 cases, the incidence of malignant tumor with VTE is 0.75%; Clinical material:76 cases of male, female 108 cases, aged 3-85 (median age 54.2 years).Accounted for 26% of 48 cases of lung cancer, the most common (2617, the total incidence of 1.8%),45 cases (24.5%) followed by gynecological tumor incidence (total 2678 cases,1.7%) 36 cases (19.6%), digestive tract tumor incidence (total 3972 cases,0.9%),18 cases (9.7%) of breast cancer incidence (total 2170 cases,0.8%),10 cases of head and neck cancer accounts for 5.4%(1689, the total incidence of 0.6%), urinary and reproductive system of male cancer 7 cases (3.8%),399, the total incidence of 1.7%), blood and lymphatic system tumors in 5 cases (2.7%) (918, the total incidence of 0.5%), other 14 cases (7.6%) of tumor incidence (total 10152 cases,0.14%); Pathological type of carcinoma in 118 cases (64%), squamous cell carcinomas 35 cases (19.2%), other types of 31 cases (16.8%); TNM staging:â…  period 6 cases, â…¡ period 25 cases, â…¢ period 51 cases, â…£period 102 cases (M0 of 17 cases of patients, 16.7%; Ml patients 85 cases,83.3%); Lower limbs thrombus type VTE152 cases (82%), upper limb VTE32 cases accounted for 82%, merge PE in 5 cases (2.7%). All of the patients by color doppler ultrasound examination and D-D detection after diagnosis, anticoagulation, thrombolysis and vena cava filter implantation treatment, such as to relieve swelling, pain symptoms, review of color doppler ultrasound thrombus disappear or partial recanalization, D-D testing standards were back to normal for improved. Among them,181 cases of symptoms improved during hospitalization,3 patients died.Conclusion:Patients with malignant tumor is a high incidence of VTE, this rate is 0.75%, lower than other literatures at home and abroad; Different tumor combined incidence of VTE, the highest incidence of lung cancer, followed by gynecological tumor, the digestive tract tumor and breast cancer, etc.; Patients with adanced tumor merger is relatively rare; The central venous catheter (PICC) peripheral venipuncture can induce upper limb VTE, the treatment effect and better prognosis than other patients; Prophylactic anticoagulation in patients with high-risk, close observation, early detection, early diagnosis and timely treatment can reduce patient pain, improve the quality of survival.
Keywords/Search Tags:malignant tumor, venous thromboembolism, Deep vein thrombosis, pulmonary embolism anticoagulant therapy
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